Pancreatic cyst surveillance imposes low psychological burden: preliminary results of the PACYFIC study

Overbeek, Kasper A.; Kamps, Anne; Riet, Priscilla Van; Marco, Mariacristina Di; Zerboni, Giulia; Hooft, Jeanin E. van; Carrara, Sandro; Ricci, Claudio; Gonda, Tamas A.; Schoon, Erik J.; Polkowski, Marcin; Beyer, Georg; Honkoop, Pieter; Waaij, Laurens van der; Casadei, Riccardo; Capurso, Gabriele; Bruno, Marco J.; Bleiker, Eveline M. A.; Cahen, Djuna L.

doi:10.1016/j.pan.2018.05.010

Cited by 2 publications

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“…For example, responses from 109 international survey participants before and during surveillance for PCLs demonstrated low psychological burden in association with surveillance. 44 Incorporation of age, surgical candidacy, and lesion size in aggregate may help patients and caregivers make joint decisions regarding length of imaging surveillance.…”

Section: Pcl Guidelines and Surveillance Strategies-current And Futur...mentioning

confidence: 99%

Pancreatic Cystic Lesions: Review of the Current State of Diagnosis and Surveillance

et al. 2022

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Pancreatic cystic lesions (PCLs) are both common and often incidental. These encompass a range of pathologies with varying degrees of concern for malignancy. Although establishing a diagnosis is helpful for determining malignant potential, many PCLs are either too small to characterize or demonstrate nonspecific morphologic features. The most salient modalities involved in diagnosis and surveillance are magnetic resonance imaging, multidetector computerized tomography, and endoscopic ultrasound. Fine needle aspiration has a role in conjunction with molecular markers as a diagnostic tool, particularly for identifying malignant lesions. Although several major consensus guidelines exist internationally, there remains uncertainty in establishing the strength of the association between all PCLs and pancreatic adenocarcinoma, and in showing a benefit from extended periods of imaging surveillance. No consensus exists between the major guidelines, particularly regarding surveillance duration, frequency, or endpoints. This review paper discusses PCL subtypes, diagnosis, and compares the major consensus guidelines with considerations for local adaptability along with questions regarding current and future priorities for research.

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Section: Pcl Guidelines and Surveillance Strategies-current And Futur...mentioning

confidence: 99%

Pancreatic Cystic Lesions: Review of the Current State of Diagnosis and Surveillance

et al. 2022

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“…Another aspect of long-term regular surveillance to consider is the psychological burden of patients undergoing it. A 2019 study of 109 patients eligible for pancreatic cyst surveillance showed that patients already undergoing surveillance had significantly more difficulty sleeping in the week before visit and found the program more burdensome ( P = 0.035 and P = 0.044, correspondingly) compared with those who had not started it yet (8). Last, postoperative morbidity in pancreatic cyst surveillance programs is not negligible even in specialized centers, with major complications (grades IIIa through IVb according to the Clavien-Dindo classification) reported in approximately one-quarter of patients undergoing resection of the pancreas (9).…”

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confidence: 99%

When to Stop Surveillance: Pancreatic Cysts

Petrov

2023

Am J Gastroenterol

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Surveillance of mucinous pancreatic cysts is a key to reducing pancreatic cancer risk and detecting malignancy early. However, while the management of cysts with high-risk and worrisome features is fairly straightforward, surveillance of patients with low-risk branch-duct intraductal papillary mucinous neoplasms has long presented gastroenterologists with the challenging question of discontinuation of surveillance. Up-to-date evidence supports the cessation of follow-up in these patients depending on both interval stability of the cyst and cyst size. Based on these criteria, discontinuation of surveillance at either 5 years or 10 years is recommended. Oversurveillance of patients with pancreatic cysts in the absence of high-risk and worrisome features is discouraged.

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Pancreatic cyst surveillance imposes low psychological burden: preliminary results of the PACYFIC study

Cited by 2 publications

References 0 publications

Pancreatic Cystic Lesions: Review of the Current State of Diagnosis and Surveillance

Pancreatic Cystic Lesions: Review of the Current State of Diagnosis and Surveillance

When to Stop Surveillance: Pancreatic Cysts

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