Pancreatic Diseases in Children

Lerner, Aaron; Branski, David; Lebenthal, Emanuel

doi:10.1016/s0031-3955(05)70400-4

Cited by 76 publications

(62 citation statements)

References 105 publications

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“…Abdominal pain is an important early symptom in children (11,12). The frequency of abdominal pain in older children, as a first symptom was similar to that of the adults, whereas in younger children, vomiting was reported as an important clinical symptom (13). The characteristics, location and triggers of abdominal pain, in addition to physical examination of the abdomen, are important clues in the diagnosis of acute pancreatitis.…”

Section: Contextmentioning

confidence: 87%

“…In severe acute pancreatitis, shock may be the initial presentation in children, followed by symptoms of multi-organ failures such as dyspnea, oliguria, hemorrhage and mental status changes (14). Pancreatitis can occur in the first decade of life following viral infections such as mumps, Epstein-Bar virus and often spontaneously resolve within one week (2,5,7,(13)(14)(15)(16)(17). These symptoms are considered as general symptoms in children, but sometimes can be easily confused with signs of other underlying diseases.…”

Section: Contextmentioning

confidence: 99%

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A Review on Acute Pediatric Pancreatitis

Kadı¹,

Dabirian²

2016

J Pediatr Rev

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Nowadays, acute pancreatitis is not a rare disease in children and adolescences and the incidence of the disease has increased in pediatric patients over the past two decades. Acute pancreatitis in children can be triggered by a wide array of factors such as drugs, infections, trauma, anatomic anomalies and metabolic disorders. The signs and symptoms of acute pancreatitis are non-specific with an age-related pattern. The most common symptoms are upper abdominal pain and vomiting. Other less common signs and symptoms include abdominal discomfort, tachycardia, fever, and hypotension, jaundice and back pain. Since the signs and symptoms of acute pancreatitis are non-specific, it should be considered during the differential diagnosis of abdominal pain in children and needs prompt treatment because it may become a life-threatening disorder. Diagnosis of acute pancreatitis is principally achieved by meeting two of the following criteria: compatible clinical symptoms including abdominal pain, nausea, vomiting, or back pain; > 3 fold increase in serum amylase and/or lipase; presence of radiographic evidence including pancreatic edema on ultrasound or computed tomography. To provide a framework to review the diagnosis in pediatrics and identify evidence-based guidelines to manage acute pancreatitis in children, the current concepts on the diagnosis and treatment of pediatric acute pancreatitis are summarized.

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Section: Contextmentioning

confidence: 87%

Section: Contextmentioning

confidence: 99%

A Review on Acute Pediatric Pancreatitis

Kadı¹,

Dabirian²

2016

J Pediatr Rev

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“…In contrast to adults in whom 80% of cases of acute pancreatitis are associated with alcoholism and biliary disease, the etiology in children is diverse. Lerner et al [8] summarized the etiological causes of acute pancreatitis in children as: idiopathic 22%, trauma 20%, infection 15%, biliary tract disease 14%, drugs 13%, miscellaneous 11% and congenital anomalies 5%.…”

Section: Discussionmentioning

confidence: 99%

Acute Pancreatitis Associated with <i>Mycoplasma pneumoniae:</i> A Case Report of Missed Diagnosis

Al-Abassi¹

2002

Med Princ Pract

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Objective: Mycoplasma pneumoniae is responsible for approximately 20% of community-acquired pneumonia. A wide variety of extrapulmonary manifestations related to M. pneumoniae infection can occur. The diagnosis of M. pneumoniae and its association with acute pancreatitis is briefly reviewed. Clinical Presentation: We describe the case of a 9-year-old boy with clinical features of acute abdomen. Intervention: A perforated appendix was suspected and the patient was accordingly operated on. The clinical, radiological and serological findings that led to the proper diagnosis are described. Conclusion: The case is presented to help increasing the awareness of M. pneumoniae infection as a potential cause of acute pancreatitis in children.

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“…En relación con la pancreatitis necrotizante, esta presenta una incidencia en niños menor del 1%, 8 mientras que los pseudoquistes representan la complicación más frecuente en niños con PA grave, con una incidencia del 10 al 17%. 9 Respecto al pronóstico, existen, a la fecha, dos predictores de gravedad de PA en niños: la lipasa sérica 10 y el puntaje de gravedad de la pancreatitis aguda pediátrica (paediatric acute pancreatitis severity; PAPS, por sus siglas en inglés), 11 que pueden ser utilizados dentro de las primeras 24 h y luego de las 48 h de su presentación, respectivamente. La tasa de mortalidad reportada en niños varía entre un 0 y un 17%, y se relaciona, generalmente, con la enfermedad sistémica subyacente o traumatismos.…”

Section: Introductionunclassified

Pancreatitis aguda grave e infección por el virus de la influenza A (H1N1) en un paciente pediátrico: reporte de caso

et al. 2015

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Arch Argent Pediatr 2015;113(4):e215-e218 / e215Presentación de casos clínicos RESUMEN La pancreatitis aguda (PA) es una enfermedad inflamatoria del páncreas caracterizada por dolor abdominal y niveles elevados de enzimas pancreáticas. Representa la enfermedad pancreática más común de niños y adultos. Para el diagnóstico, se requieren 2 de los siguientes 3 criterios: dolor abdominal característico de PA, valores séricos de amilasa y/o lipasa 3 veces mayores que el límite superior normal y hallazgos característicos en las imágenes. Múltiples etiologías se han asociado: traumatismos, enfermedades metabólicas e infecciones (mixovirus, VIH, parotiditis, coxsackie, hepatitis B, A, citomegalovirus, varicela, herpes simple). Existen solo 3 casos reportados de PA asociados al virus de la influenza H1N1, solo uno en un niño y de características no complicadas. Palabras clave: pancreatitis, pancreatitis aguda necrotizante, subtipo H1N1 del virus de la influenza A, infección, virus.ABSTRACT Acute pancreatitis is an inflammatory disease of the pancreas, characterized by abdominal pain and high level of pancreatic enzymes. Pancreatitis is the most common disease of pancreas in children and adults. For the diagnosis we need 2 of 3 characteristics: abdominal pain characteristic of acute pancreatitis, amylase and/or lipase 3 times higher than the normal upper limit and characteristic findings in images. The etiologies are multiple: trauma, metabolic disease and infections: mixovirus, HIV, measles, coxsackie, hepatitis B, C, cytomegalovirus, varicella, herpes simplex. Three cases of PA associated with H1N1 Influenza virus were reported, only one in a child with uncomplicated features.

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Pancreatic Diseases in Children

Cited by 76 publications

References 105 publications

A Review on Acute Pediatric Pancreatitis

A Review on Acute Pediatric Pancreatitis

Acute Pancreatitis Associated with <i>Mycoplasma pneumoniae:</i> A Case Report of Missed Diagnosis

Pancreatitis aguda grave e infección por el virus de la influenza A (H1N1) en un paciente pediátrico: reporte de caso

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