Pancreatic duct stents

Yi, Jin-Hui; Li, Zhao-Shen; Hu, Liang‐Hao

doi:10.1111/1751-2980.13158

Cited by 7 publications

(3 citation statements)

References 135 publications

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“…However, pancreatic stenting is now a more widely performed procedure in cases of intraductal hypertension, bypass obstructing stones, restoring lumen patency in cases with dominant, symptomatic strictures, and so on (16). Therapeutic stent placement is intended to restore the proper flow of pancreatic secretion and has demonstrated positive results in several studies of early-stage pancreatitis (17)(18)(19).…”

Section: Discussionmentioning

confidence: 99%

Endoscopic transpapillary stent placement in patients with necrotizing pancreatitis and disconnected main pancreatic duct syndrome

Shabunin,

Bagatelia,

Bedin

et al. 2023

Front. Surg.

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IntroductionPancreatic necrosis is one of the most severe acute abdominal conditions, accounting for 15%–20% of all patients with acute pancreatitis and characterized by significant rates of postoperative complications and mortality. Patients with pancreatic necrosis, in which pathological changes are localized in the proximal pancreas and retroperitoneal space, deserve special attention. This form of the disease includes patients with disconnected main pancreatic duct (MPD) syndrome who have a difficult prognosis.AimThe aim of the study was an improvement of treatment results in patients with necrotizing pancreatitis and signs of the dissociation of the pancreas duct system using the endoscopic transpapillary stent placement method.Material and methodsThis study was a retrospective cohort study. There were 32 patients with acute necrotizing pancreatitis who were managed using the endoscopic transpapillary stent placement method between 2019 and 2021. Disconnected MPD syndrome was diagnosed in all 32 patients. In total, 26 patients were admitted to hospital in the first 72 h, while 6 patients were admitted after 72 h. We diagnosed the necrotizing process located in the proximal and central areas of the pancreas and peripancreatic space in all these patients (“model III”).ResultsPositive results related to transpapillary stent placement were noted in 24 (75%) patients (first cohort). A total of 20 patients from this group were admitted to hospital in the first 48 h, and 4 patients were admitted later than 72 h from the onset of disease. Moreover, 8 patients (25%; second cohort) failed to succeed in transpapillary stent placement. Complications in the first cohort occurred in 3 (12.5%) patients: dislocation of the stent into the duodenum occurred in 1 patient, and bleeding after papillosphincterotomy took place in 2 patients. Meanwhile, infected necrotized pancreatitis developed in 5 patients, and 1 patient (5%) died. Complications among the second cohort occurred in 2 (25%) patients: erosive bleeding (after debridement). Infected necrotized pancreatitis developed in 4 patients, and 2 patients (25%) died.ConclusionsEndoscopic transpapillary stent placement is an effective minimally invasive approach in the management of patients with necrotizing pancreatitis.

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Section: Discussionmentioning

confidence: 99%

Endoscopic transpapillary stent placement in patients with necrotizing pancreatitis and disconnected main pancreatic duct syndrome

Shabunin,

Bagatelia,

Bedin

et al. 2023

Front. Surg.

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“…Endoscopic pancreatic duct stenting is useful for recurrent chronic obstructive pancreatitis 1,2 . However, approaching the caudal pancreatic duct is challenging in patients with severe stenosis or a spiral (loop type) or hairpin (reverse‐Z type) curve of the main pancreatic duct 3 .…”

Section: Brief Explanationmentioning

confidence: 99%

Case of usefulness of drill dilator for pancreatic stone disease in a reverse‐Z type main pancreatic duct

Yamamoto,

Ota,

Itani

2024

Digestive Endoscopy

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“…Chronic pancreatitis patients are often accompanied by pancreatic duct stenosis; therefore, it is necessary to implant pancreatic duct stents to dilate the pancreatic duct for safe drainage. Pancreatic duct stenting using endoscopy or surgery showed good clinical prospects for the management of benign and malignant pancreatic diseases [16][17][18]. Pancreatic duct stenting is the major treatment option for chronic pancreatitis [19,20].…”

Section: Introductionmentioning

confidence: 99%

Citric Acid Loaded Hydrogel-Coated Stent for Dissolving Pancreatic Duct Calculi

Li,

Lv,

Chen

et al. 2024

Gels

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In recent years, the incidence of chronic pancreatitis has increased significantly. Pancreatic calculi obstruct the pancreatic duct and induce abdominal pain in the patients. Pancreatic duct stenting is the major treatment option for chronic pancreatitis with calculi. In this study, a new kind of drug-eluting stent, a pancreatic stent coated by methacrylated gelatin (GelMA) hydrogel loaded with citric acid (CA), was designed for the interventional treatment of pancreatic duct calculi. The CA loading capacity reached up to 0.7 g CA/g hydrogel-coated stent. The GelMA hydrogel coating has higher mechanical strength and lower swelling performance after loading with CA. The in vitro experiments of stents exhibited good performance in CA sustained release and the calculi can be dissolved in almost 3 days. The stents also showed good blood compatibility and cell compatibility. This research has important clinical value in the treatment of chronic pancreatitis with pancreatic calculi.

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Pancreatic duct stents

Cited by 7 publications

References 135 publications

Endoscopic transpapillary stent placement in patients with necrotizing pancreatitis and disconnected main pancreatic duct syndrome

Endoscopic transpapillary stent placement in patients with necrotizing pancreatitis and disconnected main pancreatic duct syndrome

Case of usefulness of drill dilator for pancreatic stone disease in a reverse‐Z type main pancreatic duct

Citric Acid Loaded Hydrogel-Coated Stent for Dissolving Pancreatic Duct Calculi

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