1986
DOI: 10.1093/jn/116.12.2372
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Pancreatic Enzyme and Plasma Cholesterol Response to Chronic Ingestion of a Nonabsorbable Lipid in Rats

Abstract: Pancreatic enzyme activity and plasma and high density lipoprotein (HDL) cholesterol levels were measured in rats chronically fed a nonabsorbable lipid, sucrose polyester (SPE), to determine if the rat pancreas responds to SPE as a dietary lipid or a nonnutritive ingredient. Adult male rats were fed for 28 d a diet containing either 5% or 20% corn oil, 5% SPE, 16% and 4% hydrogenated palm oil (HPO), or 16% corn oil and 4% HPO. HPO is used to prevent anal leakage of unabsorbed oil when SPE is fed at high dietar… Show more

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Cited by 9 publications
(4 citation statements)
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“…Others have reported differences in the acceptability of solid and liquid, digestible and indigestible oils in rats as described in the introduction. Our results with the LTAG and SA diets are consistent with other reports showing acceptability of diets containing either palm oil [e.g., 22,23], or non-digestible oil-like substances [14][15][16][17], respectively.…”
Section: Resultssupporting
confidence: 92%
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“…Others have reported differences in the acceptability of solid and liquid, digestible and indigestible oils in rats as described in the introduction. Our results with the LTAG and SA diets are consistent with other reports showing acceptability of diets containing either palm oil [e.g., 22,23], or non-digestible oil-like substances [14][15][16][17], respectively.…”
Section: Resultssupporting
confidence: 92%
“…Instead, SA intakes were comparable to LTAG. In a study in which fatty acid deficiency was not present, the presence of 4% hydrogenated palm oil did not result in reduced intake [15]. The present study indicates that at a higher concentration, hydrogenated palm oil is not acceptable to rats, although the reason for that remains unclear.…”
Section: Resultscontrasting
confidence: 52%
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“…The question of whether the pancreas responds to olestra as a digestible dietary lipid or as a non‐nutritive ingredient was studied by Hager & Schneeman 52 . Adult rats were assigned to groups fed diets containing 5% corn oil, 20% corn oil, 16% corn oil plus 4% hydrogenated palm oil (HPO), 5% SPE, or 16% SPE plus 4% HPO for 28 days.…”
Section: Pancreatic Enzymesmentioning
confidence: 99%