2011
DOI: 10.5021/ad.2011.23.2.225
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Pancreatic Panniculitis Associated with Acinar Cell Carcinoma of the Pancreas: A Case Report

Abstract: Pancreatic panniculitis is a rare type of disorder associated with pancreatic diseases. We describe here a case of 54-year-old man who was admitted to the Department of Dermatology with the diagnosis of erythema nodosum. The patient presented with a 9-month history of painful erythematous nodules on the extremities, joint pain and swelling, and weight loss. A highly elevated level of pancreatic lipase was found on the laboratory examinations. The biopsy specimens from the skin lesions showed subcutaneous fat n… Show more

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Cited by 27 publications
(16 citation statements)
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“…2 In addition to our case, we identified in the English literature 30 well-documented cases of complete PPP syndrome associated with pancreatic carcinoma. 16,[20][21][22][23][24][25][26][28][29][30][31][32][33][34][35][36][37][38] These patients were mostly elderly men (87%) with a mean age at diagnosis of 61.2 ± 13 years (range, 20-88 years). Acinar cell carcinoma, in 58% of the cases, was the most common pancreatic neoplasm, whereas metastatic disease was documented in 21 patients.…”
Section: Literature Reviewmentioning
confidence: 99%
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“…2 In addition to our case, we identified in the English literature 30 well-documented cases of complete PPP syndrome associated with pancreatic carcinoma. 16,[20][21][22][23][24][25][26][28][29][30][31][32][33][34][35][36][37][38] These patients were mostly elderly men (87%) with a mean age at diagnosis of 61.2 ± 13 years (range, 20-88 years). Acinar cell carcinoma, in 58% of the cases, was the most common pancreatic neoplasm, whereas metastatic disease was documented in 21 patients.…”
Section: Literature Reviewmentioning
confidence: 99%
“…In cases associated with acute or chronic pancreatitis, the mortality rate was as high as 24%, 2 and when associated with pancreatic carcinoma, it was nearly 74%. [20][21][22][23][24][25][26][28][29][30][31][32][33][34][35][36][37][38] Subcutaneous nodules may be the presenting symptom of an otherwise occult pancreatic disease. In fact, Hughes et al 17 reported that panniculitis was the presenting symptom in 65% of patients with pancreatic carcinoma.…”
Section: Literature Reviewmentioning
confidence: 99%
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“…Jaundice is an infrequent finding (12%) and complications related to lipase release (panniculitis) are common. 2 Abdominal pain is reported to be present in 32% and nausea and vomiting in 23% of patients. 3 To the best of our knowledge, this is the first described case of spontaneous rupture of ACC that presented as an acute abdomen.…”
Section: Introductionmentioning
confidence: 98%
“…Pancreatic panniculitis rarely (2-3%) accompanies pancreatic disease; therefore, diagnosing the disease can sometimes be difficult (2). Physicians should include pancreatic panniculitis in the differential diagnosis of erythema nodosum.…”
mentioning
confidence: 99%