Pancreatic sarcomatoid carcinoma: An unusual evolution

Omrani, Sahir; Hajri, Mohamed; Ferjaoui, Wael; Guizani, Rami; Talbi, Ghofrane; Gharbi, Lassad; Bayar, Rached; Khalfallah, Mohamed Tahar

doi:10.15761/mcrr.1000141

Cited by 1 publication

(1 citation statement)

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“…There are two reports of exceptional survival after ten years of follow-up. One of them received adjuvant chemotherapy with gemcitabine who remained free of tumor recurrence and metastasis for 10 years but after this period the patient presented a colonic obstruction due to metastatic disease[ 18 ]. In the other case of SCP with a stage T3N1M0, after surgery the patient completed a 6-month course of adjuvant chemotherapy with gemcitabine and was then followed up with abdomen CT. At 10 years after the operation, the authors report he is alive with no recurrence[ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Sarcomatoid carcinoma of the pancreas — a rare tumor with an uncommon presentation and course: A case report and review of literature

Toledo¹,

Berger²,

Carreño³

et al. 2021

WJCC

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BACKGROUND Sarcomatoid carcinoma of the pancreas (SCP) is a rare type of pancreatic neoplasm, and only a few cases have been described in the literature. Histologically, it is composed mostly of atypical spindle cells with apparent sarcomatous features. CASE SUMMARY This is a report of a 61-year-old Chilean woman who underwent medical investigation for acute abdominal pain. Computed tomography identified a solid tumor in the tail of the pancreas with features suspicious of malignancy. En-blo c distal pancreatectomy and splenectomy were performed to excise the tumor. Histopathology and immunohistochemistry were confirmatory of sarcomatoid carcinoma with lymphovascular invasion. After surgery, the patient did not receive chemotherapy. Previous studies indicate a poor prognosis for this type of malignancy. However, our patient has survived for 35 mo with no recurrence to date. CONCLUSION The case presented herein is a patient with an SCP with a rare presentation and long-term survival after surgery despite not receiving adjuvant chemotherapy.

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Section: Discussionmentioning

confidence: 99%