Pancreatic squamous carcinoma mimicking a bleeding duodenal ulcer

Fonseca, Jorge; Brito, María José; Castro, Clara; Lopes, Lygia Vieira; Folgado, António; Murinello, F; Leal, Cunha

doi:10.1016/s0016-5107(00)70374-9

Cited by 6 publications

(7 citation statements)

References 4 publications

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“…Eight cases of squamous cell carcinoma Pancreatic have been reported in the literature since 1990 [1]- [3]. In the classification of tumors outlined by WHO [4], squamous cell carcinoma falls under adenosquamous tumor.…”

Section: Discussionmentioning

confidence: 99%

“…In CT scan, there is often a peripheral contrast in the lesion after injection of contrast [7]. These tumors, often voluminous, have grim prognosis at diagnosis, with loco regional and lymph nodeinvasion very common [8], as well as metastases, which were reported in six other cases in the literature [3] [9] [10]. Baylor et al reported a 5-year survivalrate of less than 1% [11], Beyer et al a 1-year survival of 4.8% [2].…”

Section: Discussionmentioning

confidence: 99%

“…However, loco regional andmetastastic invasionvery common, makes most tumors unressectable. Patients who undergo a curative or palliative treatment (dual or single biliodigestive bypass) surgery have a better prognosis [3]. In case of unresectable or metastatic tumor, radiation or a combination chemotherapy radiation did not prove effective [10].…”

Section: Discussionmentioning

confidence: 99%

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Squamous Cell Carcinoma of the Pancreas

Ossibi¹,

Yazough²,

Bennani³

et al. 2014

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Squamous Cell Carcinoma of the Pancreas

Ossibi¹,

Yazough²,

Bennani³

et al. 2014

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“…Cases are described in the literature only as case reports [2-11]. In view of its rarity, squamous cell carcinoma (SCC) in the pancreas is presumed to be metastatic from another primary site, until proven otherwise [1,8].…”

Section: Discussionmentioning

confidence: 99%

“…We have identified (Table 1) an additional 14 cases diagnosed ante-mortem since 2005 and a further case diagnosed ante-mortem in 2000 by Fonseca et al . [11], which was not included in the excellent review by Brown et al . [10].…”

Section: Discussionmentioning

confidence: 99%

Primary squamous cell carcinoma of the pancreas: a case report and review of the literature

et al. 2012

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IntroductionPrimary squamous cell carcinoma of the pancreas is a rare tumor with poor prognosis and is found in the literature only as case reports. The optimal management course remains poorly defined. We present a case of primary basaloid squamous cell carcinoma of the pancreas metastatic to the liver, which was treated with surgery and systemic chemotherapy. Our patient survived for 15 months: the longest survival reported in the literature to date.Case presentationA 70-year-old Caucasian man presented to hospital with a three-month history of weight loss, pruritus and icterus. Imaging studies confirmed the presence of an operable mass lesion in the head of the pancreas. Following a pancreaticoduodenectomy, histology results led us to make a diagnosis of squamous cell carcinoma. Postoperative restaging showed multiple metastases in the liver. He underwent palliative systemic chemotherapy with cisplatin and 5-fluorouracil achieving partial response and an excellent quality of life. He then went on to start second-line chemotherapy, but unfortunately died of sepsis soon thereafter.ConclusionsThis case report emphasizes that achievement of a worthwhile objective and symptomatic palliative response is possible using platinum-based chemotherapy in squamous cell carcinoma of the pancreas.

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