Pancreatic tuberculosis in an immunocompetent young female mimicking a malignant tumor: A case report and diagnostic radiological investigation

Miyamoto, Tomomi; Tone, Kazuya; Inaki, Shunsuke; Saito, Ryo; Maeda, Miku; Nagano, Yuko; Akutsu, Taisuke; Furube, Atsuki; Gochi, Mina; Motohashi, Kenji; Koido, Shigeo; Takagi, Masamichi; Kuwano, Kazuyoshi

doi:10.1016/j.clinimag.2021.09.021

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…In terms of clinical manifestations, abdominal pain was the most common symptom in patients, followed by weight loss, low fever, jaundice, or acute pancreatitis. [6,7,[17][18][19][20][21][22][23][24][25][26] We retrospectively analyzed the cases of pancreatic tuberculosis published in the past 2 years and found that except one case without abdominal pain, the other cases all showed abdominal pain. It is obviously different from low back pain caused by pancreatic cancer.…”

Section: Discussionmentioning

confidence: 99%

Pancreatic tuberculosis misdiagnosed for surgical treatment: clinical analysis of 3 cases and literature review

Zhou,

Wang,

et al. 2023

Journal of Pancreatology

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The incidence rate of pancreatic tuberculosis (PT) is low, and it is difficult to distinguish from pancreatic malignant tumor before operation. We present three patients diagnosed after surgical treatment. All three cases involved female patients who were admitted due to primary manifestation of abdominal pain. These patients did not exhibit symptoms such as jaundice or back pain, and their tumor markers were within normal range. The surgical interventions employed included partial resection of the tumor in one case, mass resection in another, and pancreaticoduodenectomy in the third. Preoperative puncture biopsy is essential for diagnosing pancreatic tuberculosis, and it should be actively conducted on patients with suspected cases. We summarize several common manifestations of pancreatic tuberculosis to find the possibility of tuberculosis during preoperative evaluation and avoid misdiagnosis and unnecessary surgery.

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Section: Discussionmentioning

confidence: 99%

Pancreatic tuberculosis misdiagnosed for surgical treatment: clinical analysis of 3 cases and literature review

Zhou,

Wang,

et al. 2023

Journal of Pancreatology

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“…EUS-FNB allows obtaining pancreatic specimens with cytopathology. Many cases have been published worldwide in the last few years with different and non-specific clinical manifestations (Table 1 )[ 5 , 7 - 10 ].…”

Section: Pancreatic Tbmentioning

confidence: 99%

Cheesy material on macroscopic on-site evaluation after endoscopic ultrasound-guided fine-needle biopsy: Don't miss the tuberculosis

Delsa¹,

Bellahammou²,

Okasha³

et al. 2023

World J Clin Cases

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Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is an excellent investigation to diagnose pancreatic lesions and has shown high accuracy for its use in pathologic diagnosis. Recently, macroscopic on-site evaluation (MOSE) performed by an endoscopist was introduced as an alternative to rapid on-site cytologic evaluation to increase the diagnostic yield of EUS-FNB. The MOSE of the biopsy can estimate the adequacy of the sample directly by the macroscopic evaluation of the core tissue obtained from EUS-FNB. Isolated pancreatic tuberculosis is extremely rare and difficult to diagnose because of its non-specific signs and symptoms. Therefore, this challenging diagnosis is based on endoscopy, imaging, and the bacteriological and histological examination of tissue biopsies. This uncommon presentation of tuberculosis can be revealed as pancreatic mass mimicking cancer. EUS-FNB can be very useful in providing a valuable histopathological diagnosis. A calcified lesion with a cheesy core in MOSE must be suggestive of tuberculosis, leading to the request of the GeneXpert, which can detect Mycobacterium tuberculosis deoxyribonucleic acid and resistance to rifampicin. A decent diagnostic strategy is crucial to prevent unnecessary surgical resection and to supply conservative management with antitubercular therapy.

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Pancreatic tuberculosis in an immunocompetent young female mimicking a malignant tumor: A case report and diagnostic radiological investigation

Cited by 2 publications

References 9 publications

Pancreatic tuberculosis misdiagnosed for surgical treatment: clinical analysis of 3 cases and literature review

Pancreatic tuberculosis misdiagnosed for surgical treatment: clinical analysis of 3 cases and literature review

Cheesy material on macroscopic on-site evaluation after endoscopic ultrasound-guided fine-needle biopsy: Don't miss the tuberculosis

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