20% to 30% progress to severe acute pancreatitis (SAP), with mortality rates ranging between 13% and 35%. 2 A majority of patients with SAP require acute care and nutritional support in an intensive care unit (ICU). 3 Early and accurate identification of SAP is crucial to reduce mortality rates and im prove clinical outcomes. 4 Therefore, it is impor tant to recognize prognostic factors and estab lish a prediction model (prognostic scoring sys tem) with high discriminatory efficiency for SAP.INTROduCTION Acute pancreatitis (AP) is one of the most common gastrointestinal diseases requiring hospitalization. It is associated with a high hospitalization cost in many countries. The global incidence of AP has risen over the last decades, with an average annual percent change of 3.07%, 1 resulting in an increased burden on health care systems. Although most patients with AP usually experience a mild disease that is self limited and lasts approximately a week, about