Pancreoprotective Effect of Jicama (Pachyrhizus erosus, Fabaceae) Fiber against High-Sugar Diet in Mice

Santoso, Putra; Maliza, Rita; Rahayu, Resti; Amelia, Astri

doi:10.3889/oamjms.2020.4528

Cited by 5 publications

(4 citation statements)

References 27 publications

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“…Soluble fibre causes a slower gastric emptying rate and increases the viscosity of digested food in the intestine, thereby reducing glucose absorption. As a result, the amount of glucose that reaches the portal vein is lower (Santoso et al, 2020). In addition, fibre can also be fermented by intestinal microbes to produce short-chain fatty acids, including acetate, butyrate, and propionate.…”

Section: Pancreas Histologymentioning

confidence: 99%

Consumption of Cassava Extract (Manihot Esculenta) Improves Pancreatic Histology and Seminiferous Tubules in Wistar Rats Induced Diabetes Mellitus with Streptozotocin

Prasetyo,

Ghalib,

Ahsani

et al. 2023

jika

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Diabetes Mellitus (DM) can damage various organs, which are the pancreas and the testes, which cause infertility. Therefore, alternative treatment is needed, including cassava (Manihot Esculenta) which contains polyphenol antioxidants that can reduce free radicals caused by hyperglycemia. The objectives of the study were to determine the effect of cassava consumption on the histological pancreas and testes of Wistar rats induced with streptozotocin. This study was an experimental study posttest only control group design. Experimental animals were divided into four treatment groups, namely healthy controls (K1), DM aqua dest (K2), DM metformin (K3), and DM cassava (K4). The treatment was given after successful DM induction. The histology of the pancreas was the area of the islets of Langerhans. The histology of the testes was the thickness of the seminiferous tubule epithelium. The analysis used a one-way ANOVA test. The average area of Langerhans Island, respectively, namely 6482,95±117.71 µm2, 2597.49±137.25 µm2, 2746.93± 172.07 µm2, and 3307.00 ± 368.51 µm2 (p-value = 0.000). The mean epithelial thickness of the seminiferous tubules was 19.62±1.12 µm, 15.59 ±0.46µm, 17.05±1.42µm, and 18.09±0.52µm (K4) (p-value = 0.000). In conclusion, the consumption of cassava extract (Manihot esculenta) can improve the histological picture of the pancreas and increase the thickness of the seminiferous tubule.

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Section: Pancreas Histologymentioning

confidence: 99%

Consumption of Cassava Extract (Manihot Esculenta) Improves Pancreatic Histology and Seminiferous Tubules in Wistar Rats Induced Diabetes Mellitus with Streptozotocin

Prasetyo,

Ghalib,

Ahsani

et al. 2023

jika

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show abstract

“…A study on male Bagg and Albino (BALB/c) mice with a treatment of tuber fibers resulted in a significant reduction in blood glucose levels [ 62 ]. In a recent study, the pancreatic tissue was also found to be protected from high fat diet-induced islet hyperplasia and hypertrophy in BALB mice treated with tuber powder [ 63 , 64 ]. Probiotic yogurt made from the P. erosus tuber was also found to be effective in decreasing blood glucose in DDY strain mice when compared with normal probiotic yogurt [ 65 ].…”

Section: Bioactivities (In Vitro and In Vivo)mentioning

confidence: 99%

The Bioactivity and Phytochemicals of Pachyrhizus erosus (L.) Urb.: A Multifunctional Underutilized Crop Plant

2021

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Pachyrhizus erosus (L.) Urb. is an underutilized crop plant belonging to the Fabaceae family. In recent years, the plant received huge attention and was introduced in different countries owing to properties such as a high nutritional content, its nitrogen-fixing abilities, and different biological activities such as its antioxidant, immune modulation, anticancer, anti-diabetes, anti-osteoporosis, antiviral, and antiaging affects, among others. In this review, an attempt has been made to comprehensively compile the biological activities of the plant to provide a panoramic view of the current efforts and further directions, which may lead to the development of pharmacological applications. This information will be helpful in creating interest towards P. erosus and it may be useful in developing the plant for medical applications and/or as a functional food. More than 50 phytochemicals have been reported from the plant, which belong to different chemical classes such as triterpenoids, organic acid, flavonoids, and fatty acids. Numerous biological activities were reported from the plant through in vivo, in vitro, ex vivo, and human studies. However, well-defined clinical studies are still lacking for the establishment of any biological properties that could be further developed. Suggestions for the further development of P. erosus, according to current knowledge about the different biological properties, has also been provided.

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“…Jicama, or yam bean (Pachyrhizus erosus (L.) Urban), is a widely produced crop in Indonesia (Santoso et al, 2020). It can be integrated into marginal farming systems in drought-prone locations, such as Sub-Saharan Africa (Buckman et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Utilization of Cassava-Jicama Composite Flour in Making Gluten-Free Biscuits with Different Types of Fats

Richirose,

Soedirga

2023

Caraka Tani J. Sustain. Agric.

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Biscuits are a commonly consumed bakery product typically using wheat flour as a primary ingredient, rendering them unsuitable for gluten-intolerant consumers. Using cassava as a gluten-free alternative for composite flour in bakery products has been proven effective. Furthermore, jicama, which has high total dietary fiber contents, including inulin, can enhance total dietary fiber content. However, high-fiber ingredients can often produce a tough texture. To address this, fats such as butter and margarine are typically used to enhance the texture of baked products, although the use of shortening still needs to be explored. Both margarine and shortening are vegetable-based, making them more widely consumable. The production of jicama flour and gluten-free biscuits was the focus of this study. This study uses a completely randomized design with two factors: the ratio of composite flour (100:0, 90:10, 80:20, 70:30, 60:40) and the type of fat (margarine and shortening). Analyses were performed on the gluten-free biscuits to determine the total dietary fiber, inulin, fat, moisture, spread ratio, color and hardness. Results indicated that biscuits made with shortening with a flour ratio of 90:10 of cassava to jicama flour are the best formulation, yielding 2.54±0.00% inulin, 6.50±0.10% total dietary fiber, 19.88±0.17% fat, 2.20±0.10% moisture content, 10.03±0.20 spread ratio, lightness (L*) value of 52.53±0.37, °Hue value of 66.78±0.51, and 869.88±16.07 g hardness. This study shows that jicama flour can be an alternative to producing composite flour for gluten-free products. Shortening, which is not commonly used in biscuit making, may be considered an alternative fat source.

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Pancreoprotective Effect of Jicama (Pachyrhizus erosus, Fabaceae) Fiber against High-Sugar Diet in Mice

Cited by 5 publications

References 27 publications

Consumption of Cassava Extract (Manihot Esculenta) Improves Pancreatic Histology and Seminiferous Tubules in Wistar Rats Induced Diabetes Mellitus with Streptozotocin

Consumption of Cassava Extract (Manihot Esculenta) Improves Pancreatic Histology and Seminiferous Tubules in Wistar Rats Induced Diabetes Mellitus with Streptozotocin

The Bioactivity and Phytochemicals of Pachyrhizus erosus (L.) Urb.: A Multifunctional Underutilized Crop Plant

Utilization of Cassava-Jicama Composite Flour in Making Gluten-Free Biscuits with Different Types of Fats

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