PANCYTOPENIA – CLINICAL & HAEMATOLOGICAL STUDY AT TERTIARY CARE CENTRE.

Abstract

Introduction: Pancytopenia is the simultaneous presence of anaemia, leucopoenia and thrombocytopenia. This study was carried out to evaluate bone marrow findings in patients with pancytopenia. Materials and Methods: This is retrospective study carried out on 100 pancytopenia patient over the period of two years. Peripheral blood smears (PBS), Bone marrow aspiration (BMA) & Trephine Biopsy slides were retrieved from storage. Data analysed was compared with various studies published in literature Results: The maximum cases of pancytopenia were in the age group up to 20 years with male preponderance. Megaloblastic anaemia (43%) was found to be most common aetiology of pancytopenia and followed by iron deficiency anaemia (23%). Conclusion: Present study concludes that basic primary haematological investigations along bone marrow aspiration/trephine bone biopsy in the pancytopenia patients are helpful in understanding the disease process. This plays a key role in planning the further management.