Pandemic influenza A(H1N1) 2009 and respiratory syncytial virus associated hospitalizations

Risk Factors for Severe Influenza A–Related Pneumonia in Adult Cohort, Mexico, 2013–14

“…We compared data for the 2013–14 cohort with data from patients 15–71 years of age with confirmed influenza A(H1N1)pdm09 infection admitted to Hospital Central during the 2009–10 pandemic ( 7 ). Patients were evaluated according to a clinical questionnaire ( 6 , 7 ); blood samples (laboratory tests and cultures), sputum samples or tracheal aspirates (Gram stain and culture), and chest radiographs were also evaluated.…”

“…We compared data for the 2013–14 cohort with data from patients 15–71 years of age with confirmed influenza A(H1N1)pdm09 infection admitted to Hospital Central during the 2009–10 pandemic ( 7 ). Patients were evaluated according to a clinical questionnaire ( 6 , 7 ); blood samples (laboratory tests and cultures), sputum samples or tracheal aspirates (Gram stain and culture), and chest radiographs were also evaluated. Nasopharyngeal or tracheal samples were analyzed to detect influenza virus by using real-time reverse transcription PCR (Laboratorio Estatal de Salud Pública, Servicios de Salud del Estado de San Luis Potosí) or sequence-specific primer PCR (Universidad Autónoma de San Luis Potosí) with previously reported primers ( 8 ).…”

Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil and Zedoary Turmeric Oil in vivo

“…Nevertheless, the excessive acute inflammation can be lethal (Zhou and Jiang, 2006). For example, after virus infection, the viral pneumonia (Lovato-Salas et al, 2010;Lee et al, 2011;Li et al, 2011), sequent bacterial pneumonia (Lee et al, 2010;Crystal et al, 2011), sequent encephalitis (Klopfleisch et al, 2007;Chen et al, 2010), and sequent angiocardiopathy (Mamas et al, 2008;Charlotte et al, 2009) were always the principal cause of the death. Hence, to protect the life quality of patients from the infection and its subsequent inflammatory complication, especially the acute inflammation, weights as much as irritant exclusion.…”

A Novel Influenza Virus Hemagglutinin-Respiratory Syncytial Virus (RSV) Fusion Protein Subunit Vaccine against Influenza and RSV

“…nfluenza virus and respiratory syncytial virus (RSV) may cause respiratory tract illness in individuals of all ages, but they have particular impact on the young and the elderly (1)(2)(3)(4). Annually, 3 to 5 million people worldwide are infected by influenza virus, with more than 250,000 of those cases resulting in death (5).…”

“…Additionally, severe infection of the lower respiratory tract has been associated with asthma and recurrent wheezing in RSV-infected children (10,11). Notably, both viruses may cocirculate during the autumn through winter months in the United States (2,12,13), where peak influenza infections occur between November and April, while peak RSV infections occur between late September and April (14)(15)(16)(17). Since both of these viruses cause substantial morbidity and disease, having a vaccine that protects against both viruses would be valuable.…”