Panorama Epidemiológico Da Dengue No Município De Ariquemes, Rondônia, Amazônia Ocidental, 2002 a 2011

Borges, Rodrigo De Almeida; Ramos, Lucas Feksa; Zan, Renato André; Meneguetti, Naila Fernanda Sbsczk Pereira; Meneguetti, Dionatas Ulises de Oliveira

doi:10.17058/reci.v4i4.4650

Cited by 1 publication

(2 citation statements)

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“…There is no scientific evidence to prove their pharmacological potential so far, but the applicability of the genus Aspidosperma in malaria and dengue treatment has been recently discussed (Henrique et al 2010). Malaria remains a common disease among populations living in the Amazon, probably due to continuous colonization processes (Borges et al 2015). In addition, the environmental conditions in the Amazon favor the faster completion of the reproductive cycle of malaria vectors such as mosquitoes belonging to the genus Anopheles, as well as the proliferation of protozoa belonging to the genus Plasmodium, mostly the species Plasmodium falciparum, P. malaria and P. vivax which are the causal agents of this disease (Monteiro et al 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Nevertheless, dengue is caused by one of the most frequent arbovir uses belonging to family Flaviviridae and genus Flavivirus (serotypes: DEN-1, DEN-2, DEN-3 and DEN-4). The virus is transmitted the Aedes aegypti mosquito and has high incidence in the Amazon region throughout the rainy period (Borges et al 2015). Therefore, studies are needed that point out ways to combat these diseases.…”

Section: Introductionmentioning

confidence: 99%

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Characterizing Casca d´anta: an Apocynaceae used to treat tropical diseases in the Amazonian region

Larocca

Silva

Júnior

et al. 2019

Idesia

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Aspidosperma macrocarpon Mart. (Apocynaceae) is used in popular medicine to treat malaria and dengue. The aim of the present study was to morphoanatomically, histochemistry and phytochemically characterize A. macrocarpon young branches and leaves, seeking to indicate secondary compounds presenting medicinal potential to treat these diseases. Aspidosperma macrocarpon young branches and leaves were collected in private properties located in municipality of Alta Floresta, Mato Grosso State, Brazil. Sectional and paradermic sections were set freehand using a steelblade, were doubly stained and assembled on histological slides. The fresh material was subjected to histochemical and phytochemical tests for detection of saponins, tannins, alkaloids, flavonoids, cardiotonic glycosides, anthraquinone, steroids and terpenes. Aspidosperma macrocarpon presented glandular trichomes, cavities and secretory cells. We detected the presence of tannins, flavonoid, phenolic compounds, cardiotonic glycosides and alkaloids, which may confer antiplasmodic activity and antiviral properties to the species. As far as it is known, the present study was the first to identify aspects of the histochemical and phytochemical composition of young branches and leaves A. macrocarpon which may be associated with the popular use of this plant to treat malaria and dengue in a transition region between the Cerrado and Amazon biomes, where malaria and dengue occur endemically.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%