Panretinal Photocoagulation Versus Ranibizumab for Proliferative Diabetic Retinopathy: Patient-Centered Outcomes From a Randomized Clinical Trial

Desapriya, Ediriweera B. R.; Khoshpouri, Pegah; Al-Isa, Abdulwahab Naser

doi:10.1016/j.ajo.2017.01.035

Cited by 1 publication

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References 18 publications

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“…Photocoagulation causes destruction of photoreceptors in the peripheral retina, decreasing oxygen consumption and metabolic demand. PRP will subsequently increase the oxygen flow from the choroid to the inner retina 14. This retinal restoration may decrease PDR and DME.…”

Section: Discussionmentioning

confidence: 99%

<p>Evaluation Of The Timing Of Intravitreal Bevacizumab Injection As Adjuvant Therapy To Panretinal Photocoagulation In Patients With Diabetic Macular Edema Secondary To Diabetic Retinopathy</p>

Kartasasmita

Harley²

2019

OPTH

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ObjectiveTo evaluate the difference in intravitreal bevacizumab (IVB) injection timing as adjuvant therapy to panretinal photocoagulation in patients with diabetic retinopathy combined with diabetic macular edema.MethodsThis was a retrospective nonrandomized study. Forty eyes with severe non-proliferative diabetic retinopathy (NPDR) or proliferative diabetic retinopathy (PDR) were divided into two groups; the IVB injection prior to, or after, panretinal photocoagulation. Changes in central macular thickness between the two groups were measured.ResultsThere was no significant difference in change in central macular thickness between two groups after treatment (p=0.66), neither in eyes with severe NPDR groups (p=0.48) nor eyes with PDR (p=0.82).ConclusionIVB injection after panretinal photocoagulation gives insignificant difference in changes in central macular thickness with injection prior to laser treatment in patients with diabetic retinopathy combined with diabetic macular edema.

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Section: Discussionmentioning

confidence: 99%