PANSS factors and scores in schizophrenic and bipolar disorders during an index acute episode: a further analysis of the cognitive component

Daneluzzo, E.; Arduini, Luca; Rinaldi, Osvaldo; Domenico, Monia Di; Petruzzi, Concetta; Kalyvoka, Artemis; Rossi, Alessandro

doi:10.1016/s0920-9964(01)00277-8

Cited by 48 publications

(32 citation statements)

References 36 publications

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“…Others also found that the cognitive factor correlated highly with the positive symptom factor [27]. These findings, along with our results linking the cognitive factor with verbal abilities and memory, suggest that clinician ratings of positive symptom expression may be influenced by the neurocognitive processes underlying the cognitive factor.…”

Section: Discussionsupporting

confidence: 84%

Neuropsychological Correlates of the PANSS Cognitive Factor

Ehmann

Khanbhai²,

MacEwan³

et al. 2004

Psychopathology

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Objective: Factor analytic studies of the Positive and Negative Syndrome Scale (PANSS) have consistently isolated a factor that is frequently labeled as ‘cognitive’. The present study sought to further explore the factor by examining the relationships between 4 versions of the cognitive factor and a set of neuropsychological tests. Method: Thirty-seven inpatients diagnosed with schizophrenia or schizoaffective disorder were assessed with the PANSS and neuropsychological measures. Results: Verbal intelligence and verbal memory were found to be most closely associated with cognitive factor scores. A global rating of illness severity showed greater relationships to cognitive variables than any cognitive factor. Conclusions: The PANSS cognitive factor may reflect verbal ability and memory, but is not sufficiently comprehensive to be considered as a replacement for direct assessment of cognitive functioning.

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Section: Discussionsupporting

confidence: 84%

Neuropsychological Correlates of the PANSS Cognitive Factor

Ehmann

Khanbhai²,

MacEwan³

et al. 2004

Psychopathology

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“…There are, however, studies using PANSS among acute admissions and among patients with bipolar disorders, for example, and serious validity problems have not been reported (80,175). Also, its face validity was good, and in unpublished material from a psychiatric intensive care unit, excellent inter-rater reliability was found in assessing 12 consecutively admitted in-patients (102).…”

Section: Physician Assessmentmentioning

confidence: 99%

Drugs of abuse among acute psychiatric and medical admissions: laboratory based identification of prevalence and drug influence

Mordal

Bramness

Holm

et al. 2008

General Hospital Psychiatry

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“…Esses dados apontam que a presença de sintomatologia aguda interfere no nível de discernimento do indivíduo. De fato, dados coletados de estudos, pela presente revisão, mostram uma relação direta entre menor insight no TB e uma gravidade do episódio afetivo 36,49,59,64 ou da quantidade de sintomas maníacos 17,30,32,47 . De forma semelhante, pacientes com doença de Alzheimer apresentam piora da consciência do déficit com a progressão da doença e consequente aumento da gravidade clínica 79,80 .…”

Section: Discussionunclassified

“…Dezessete estudos 11,[22][23][24][25][29][30][31][32][33][34][35][36][37][38][39][40] Três estudos investigaram a relação entre insight e a ocorrência prévia de sintomas psicóticos 17,46,50 . Um deles 50 relatou que menor insight sobre a doença estava associado a uma história de sintomas psicóticos.…”

Section: Comparação Entre O Tb E Outros Transtornos Mentaisunclassified

O insight no transtorno bipolar: uma revisão sistemática

Silva

Mograbi²,

Landeira-Fernández

et al. 2014

J. bras. psiquiatr.

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rESUMo objetivos: Realizar uma revisão sistemática para compreender que fatores estão relacionados a uma maior ou menor consciência de morbidade no transtorno bipolar (TB), como o insight varia em função do estado afetivo e estabelecer uma comparação com outros transtornos mentais. Métodos: Realizou-se uma revisão sistemática da literatura científica sobre o insight em pacientes com TB. Foram buscados estudos clínicos originais sobre o tema nas bases de dados Medline, ISI e SciELO. Os termos de busca empregados foram: "insight" OR "awareness" AND "bipolar" OR "mania" OR "manic". resultados: Foram selecionados 55 artigos. O insight no TB parece ser mais prejudicado do que na depressão unipolar, porém menos do que na esquizofrenia. Com relação ao TB, um menor nível de insight está relacionado à presença de sintomas psicóticos e de alterações cognitivas. Além disso, um comprometimento do insight está associado a uma menor adesão ao tratamento. Por outro lado, uma maior preservação do insight pode estar associada a maior ideação suicida. Finalmente, a fase maníaca cursa com um nível inferior de insight quando comparada à fase depressiva ou de eutimia. Conclusão: No TB, o insight está significativamente prejudicado, especialmente na mania. Diversos fatores clínicos parecem influenciar o nível de insight. aBStraCt objectives: To conduct a systematic review to understand which factors are related to insight in bipolar disorder (BD), how insight varies depending on affective state and to establish a comparison between BD and other mental disorders. Methods: We performed a systematic review of the scientific literature on insight in BD patients. Clinical studies on the topic were searched in the Medline, SciELO and ISI databases. The search terms used were: "insight" OR "Awareness" AND "bipolar" OR "mania". results: Fifty-five articles were selected. Insight in BD is more compromised than in unipolar depression, but less than in schizophrenia. A lower level of insight is related to the presence of psychotic symptoms and cognitive disorders. Moreover, insight impairment is associated with lower adherence to treatment. On the other hand, a greater preservation of insight may be associated with increased suicidal ideation. Finally, the manic phase is characterized by a lower level of insight than the depressive phase or euthymia. Conclusion: Insight is greatly impaired in BD, especially during mania. Several clinical factors seem to influence the level of insight.

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PANSS factors and scores in schizophrenic and bipolar disorders during an index acute episode: a further analysis of the cognitive component

Cited by 48 publications

References 36 publications

Neuropsychological Correlates of the PANSS Cognitive Factor

Neuropsychological Correlates of the PANSS Cognitive Factor

Drugs of abuse among acute psychiatric and medical admissions: laboratory based identification of prevalence and drug influence

O insight no transtorno bipolar: uma revisão sistemática

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