Papaverine inhibits biliary excretion of lipids independently of effects on bile salts secretion in isolated perfused rat liver.

Hayakawa, Tohru; Katagiri, Kenji; Kumai, Tomoyuki; Ohiwa, Takayuki; Nakai, T; Ohnishi, Hirohide; Okayama, Yasutaka; Hoshino, Makoto; Tsukada, K; Miyaji, Makoto; Takeuchi, Toshihisa

doi:10.2957/kanzo.31.1359

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Hormonal and Second Messenger Regulation1

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1991

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“…Thus CAMP appears to selectively enhance certain aspects of the secretory process but inhibits others. In contrast, preliminary studies suggest that cGMP inhibits biliary lipid excretion (138).…”

Section: Hormonal and Second Messenger Regulationmentioning

confidence: 97%

Mechanisms and regulation of bile secretion

1991

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The physiological process of bile secretion has been studied extensively and is the subject of many reviews (1-7). During the past few years, several new aspects have been explored, including cellular mechanisms, hormonal regulation and contributions from nonparenchymal (bile ductular) cells. This review focuses on these more recent developments in our understanding of the mechanisms and regulation of bile formation. THE HEPATOCYTE AS A POLARIZED EPITHELIAL CELL

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Section: Hormonal and Second Messenger Regulationmentioning

confidence: 97%