Papel do Jejum Intermitente e da Dieta Restrita em Carboidratos na Prevenção de Doenças Cardiovasculares em Pacientes Pré-Diabéticos

Khalfallah, Mohamed Tahar; Elnagar, Basma; Soliman, Shaimaa; Eissa, Ahmad; Allaithy, Amany

doi:10.36660/abc.20220606

Cited by 5 publications

(3 citation statements)

References 41 publications

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“…Thus, it was suggested that longer and larger studies are highly required to verify the differences between the group focused on body weight and the group evaluating blood glucose [ 33 ]. Lastly, Khalfallah et al examined the efficacy of both IF and low-carb diet (LCD) on microvascular and macrovascular outcomes in prediabetic patients [ 34 ]. This study demonstrated a significantly greater reduction in body weight, BMI, waist circumference, and fat percentage in group I (IF–LCD); however, no significant difference in visceral fat or skeletal muscle percentage between the two groups was noted [ 34 ].…”

Section: Resultsmentioning

confidence: 99%

Chrononutrition in the Prevention and Management of Metabolic Disorders: A Literature Review

Mentzelou,

Papadopoulou,

Psara

et al. 2024

Nutrients

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Background: The concept of time-restricted eating (TRE) or time-restricted feeding (TRF) promotes daily periods of feeding and fasting to determine whole-body physiology. Chronic misalignment of circadian rhythms or chrono-disruption is related to an increased risk of diverse metabolic disorders. The progression of non-communicable diseases seems to be affected by the timing of meals. As a result, intermittent fasting is a promising approach for their management. The aim of the present literature review is to examine and scrutinize the TRE protocols in the fields of prevention and management of metabolic disorders. Methods: This is a thorough literature review of the reported associations among circadian rhythm, metabolic disorders, diabetes mellitus, obesity, TRE, TRF, dietary habits, circadian disruption, cardiovascular diseases, atherosclerosis, and non-alcoholic fatty liver to find the already existing clinical studies from the last decade (2014–2024) in the most precise scientific online databases, using relevant specific keywords. Several inclusion and exclusion criteria were applied to scrutinize only longitudinal, cross-sectional, descriptive, and prospective clinical human studies. Results: The currently available clinical findings remain scarce and suggest that chrononutrition behaviors such as TRE or TRF may promote several metabolic benefits, mainly in body weight control and fat loss. Improvements in glucose levels and lipid profiles are currently quite controversial since some clinical studies show little or no effect. As far as liver diseases are concerned, the efficacy of intermittent fasting seems to be stronger in the management of non-alcoholic fatty liver disease due to body weight decline and fat loss. Conclusions: Even if there has been a gradual increase in clinical studies in the last few years, providing promising perspectives, currently, there is no conclusive evidence for the role of chrononutrition in metabolic disorders. Future studies should be well-designed with longer duration and larger sample sizes. Moreover, it is important to examine the best timing of the eating window and its feasibility.

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Section: Resultsmentioning

confidence: 99%

Chrononutrition in the Prevention and Management of Metabolic Disorders: A Literature Review

Mentzelou,

Papadopoulou,

Psara

et al. 2024

Nutrients

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“…Diversos desses estudos constataram que o JI resultou em emagrecimento após a intervenção com a realização do jejum intermitente, em suas diferentes modalidades (Carter et al, 2018. Corley et al, 2018Khalfallah et al, 2023;Schroderet al, 2021).…”

Section: Schroder Et Al 2021unclassified

O impacto do jejum intermitente em pessoas com diabetes

Faria,

Cabral,

Dias

2024

RSD

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O objetivo do presente trabalho foi avaliar o impacto do jejum intermitente em pessoas com diabetes do tipo 2. O tipo de estudo abordado é uma revisão integrativa, que analisa os resultados apresentados nos estudos de caso em humanos coletados nas bases de dados da PubMED, Googledocs, Ebsco entre outros. Foram utilizados os descritores: jejum intermitente, diabetes, obesidade, jejum intermitente na diabetes, intermittent fasting, diabetes, obesity,intermittent fasting in diabetes. Foram incluídos artigos publicados nos últimos 10 anos e foram consultadas cerca de 23 referências. O jejum intermitente (JI) mostrou-se benéfico no tratamento da diabetes tipo 2, resultando em redução do peso corporal, melhora do controle glicêmico e possivelmente na da doença. Embora os estudos sejam limitados, há evidências preliminares sugerindo benefícios na redução do peso e na melhoria dos níveis de glicose no sangue. No entanto, são necessários estudos de longo prazo para avaliar completamente os benefícios e riscos dessa abordagem.

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“…Therefore, there is a growing interest in exploring lifestyle interventions [4,16,17], such as intermittent fasting (IF), as an effective approach in managing T2DM risk parameters [18][19][20][21][22][23][24][25][26][27]. IF involves periods of reduced or no caloric intake alternated with periods of normal or increased caloric intake.…”

Section: Introductionmentioning

confidence: 99%

Understanding Type 2 Diabetes Mellitus Risk Parameters through Intermittent Fasting: A Machine Learning Approach

Shazman

2023

Nutrients

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Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by elevated blood glucose levels. Despite the availability of pharmacological treatments, dietary plans, and exercise regimens, T2DM remains a significant global cause of mortality. As a result, there is an increasing interest in exploring lifestyle interventions, such as intermittent fasting (IF). This study aims to identify underlying patterns and principles for effectively improving T2DM risk parameters through IF. By analyzing data from multiple randomized clinical trials investigating various IF interventions in humans, a machine learning algorithm was employed to develop a personalized recommendation system. This system offers guidance tailored to pre-diabetic and diabetic individuals, suggesting the most suitable IF interventions to improve T2DM risk parameters. With a success rate of 95%, this recommendation system provides highly individualized advice, optimizing the benefits of IF for diverse population subgroups. The outcomes of this study lead us to conclude that weight is a crucial feature for females, while age plays a determining role for males in reducing glucose levels in blood. By revealing patterns in diabetes risk parameters among individuals, this study not only offers practical guidance but also sheds light on the underlying mechanisms of T2DM, contributing to a deeper understanding of this complex metabolic disorder.

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Papel do Jejum Intermitente e da Dieta Restrita em Carboidratos na Prevenção de Doenças Cardiovasculares em Pacientes Pré-Diabéticos

Cited by 5 publications

References 41 publications

Chrononutrition in the Prevention and Management of Metabolic Disorders: A Literature Review

Chrononutrition in the Prevention and Management of Metabolic Disorders: A Literature Review

O impacto do jejum intermitente em pessoas com diabetes

Understanding Type 2 Diabetes Mellitus Risk Parameters through Intermittent Fasting: A Machine Learning Approach

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