Paper – a potential platform in pharmaceutical development

Chen, Yi‐Hsun; Kuo, Zong-Keng; Cheng, Chao‐Min

doi:10.1016/j.tibtech.2014.11.004

Cited by 52 publications

(33 citation statements)

References 42 publications

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“…Algorithm is binarizing + Hough transform + thinning + decision tree . (d) The illustration of possible combination of smartphone ultrasound device and imaging processing algorithms as an ovulation detection device…”

Section: Poc Ovulation Detection Devicesmentioning

confidence: 99%

Detection of ovulation, a review of currently available methods

Wei

et al. 2017

Bioengineering & Transla Med

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153

111

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The ability to identify the precise time of ovulation is important for women who want to plan conception or practice contraception. Here, we review the current literature on various methods for detecting ovulation including a review of point‐of‐care device technology. We incorporate an examination of methods to detect ovulation that have been developed and practiced for decades and analyze the indications and limitations of each—transvaginal ultrasonography, urinary luteinizing hormone detection, serum progesterone and urinary pregnanediol 3‐glucuronide detection, urinary follicular stimulating hormone detection, basal body temperature monitoring, and cervical mucus and salivary ferning analysis. Some point‐of‐care ovulation detection devices have been developed and commercialized based on these methods, however previous research was limited by small sample size and an inconsistent standard reference to true ovulation.

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Section: Poc Ovulation Detection Devicesmentioning

confidence: 99%

Detection of ovulation, a review of currently available methods

Wei

et al. 2017

Bioengineering & Transla Med

Self Cite

153

111

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“…13 Paper as a substrate for a cell culture platform and its emerging biomedical applications has been well reviewed by Dr Xu 14 and Dr Cheng. 15 Although distinct stacking and destocking procedure to build a 3D culture model demonstrated the potential of paper-based devices for cell-based studies, it is of importance to observe that the paper of choice is limited to certain types of paper; the most popular are Whatman brand 114 chromatography lter paper (CFP-114) and lens paper (LP). Whatman CFP-114 paper is quite thick ($200 mm), and this affects microscopy studies.…”

Section: -3mentioning

confidence: 99%

Redefining Chinese calligraphy rice paper: an economical and cytocompatible substrate for cell biological assays

Zhou

Liu

et al. 2017

RSC Adv.

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Paper is a permeable porous material composed of a solid network of fibers. It is cheap, abundant, disposable and recyclable and has self-powered fluid wicking properties that are useful in building analytical devices. Paper-based cell assays are still in their infancy compared with enzyme-and proteinbased analyses. For the first time, we show the potential of rice paper (an organic paper specifically used in Chinese calligraphy) for building cell analysis platforms. Rice paper's solution wicking and surface characterizations prove that it has a similar chemical configuration as that of a standard Whatman filter paper. Moreover, lactate dehydrogenase (LDH) release assay and WST-1 cell growth assay show that rice paper has better cell-compatibility features and improved cell distribution. The cell anchors and spreads along the cellulose fiber of the rice paper, whereas the porous rice paper matrix provides a sufficient surface area for cell growth. Cell-based immunohistochemistry was conducted to measure the expression of O-linked N-acetylglucosamine (O-GlcNAc) protein on prostate cancer cell DU145. An enhanced colorimetric signal was observed from cells grown on rice paper-based cell culture platform than those grown on 2D culture dish. The feasibility of fabricating rice paper with both direct crafting and wax printing-as well as on-paper cell immunoassays for on-demand applications-confirms the potential of rice paper as a new substrate for building paper devices for cell biology studies.

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“…The latter concept is an approach that the innate immune system uses to detect pathogens. [131][132][133] Fluidics-based platforms made out of paper (i.e., paper-based microfluidics) or other low-cost materials (e.g., cotton) that precisely manipulate tiny body fluid volumes can be used for rapid and accurate medical or healthcare diagnosis. One example of the pattern recognition receptors (PRR) is mannose binding lectin (MBL), which is a trimeric protein that can further form a higher order of complex forms among trimers.…”

Section: Perspectivesmentioning

confidence: 99%

Glycan-based diagnostic devices: current progress, challenges and perspectives

Wang

Cheng

2015

Chem. Commun.

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Diagnosis is an essential launching point for accurate medical treatment, and rapid and accurate diagnostic approaches have become the increasingly vital goal inspiring developments in a variety of analytical methods. With increasing attention in the area of glycosciences, the roles that carbohydrates play in many diseases have been elucidated, and the use of carbohydrates as disease biomarkers has become an emerging diagnostics strategy. This review article does not intend to comprehensively include all carbohydrate-related diagnostics studies. We do, however, wish to describe carbohydrate recognition and the design of sensitive detecting devices, especially those developed recently, so that readers might better grasp the principles behind such devices and relevant detection strategies, particularly those favoring inexpensive, rapid, and point-of-care (POC) approaches.

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Paper – a potential platform in pharmaceutical development

Cited by 52 publications

References 42 publications

Detection of ovulation, a review of currently available methods

Detection of ovulation, a review of currently available methods

Redefining Chinese calligraphy rice paper: an economical and cytocompatible substrate for cell biological assays

Glycan-based diagnostic devices: current progress, challenges and perspectives

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