Paper-based colorimetric glucose sensor using Prussian blue nanoparticles as mimic peroxidase

Prussian Blue Sensor for Bacteria Detection in Personal Protection Clothing

“…PB’s biocompatibility is mainly due to the bond between its cyano groups and iron ions, preventing any negative impact on cells [ 19 , 36 ]. Along with that, in contrast with other research works where PB is synthesised as nanoparticles and used as a sensor for diverse applications [ 29 , 37 ], our study demonstrated the functionality of commercial PB used as is, facilitating the acquisition of the functional molecule without the need for a complex synthesis.…”

Advances and perspectives of nanozymes in respiratory diseases

“…[47][48][49][50][51] In these peroxidase-like nanozyme-catalyzed systems, substrates such as 3,3 0 ,5,5 0 -tetramethylbenzidine, 2,2 0 -azinobis-3-ethyl-benzothiazoline-6-sulfonic acid, o-phenylene-diamine dihydrochloride, Trinder's reagents, terephthalic acid, luminol, and others are often applied to generate signal products in the presence of H 2 O 2 . [52][53][54][55][56][57] The mechanisms of most peroxidase-like nanozymes are to decompose H 2 O 2 into hydroxyl radicals ( OH) and then further oxidize substrates. 58,59 Currently, most works on peroxidase-like nanozymes mainly focus on the aspects of the fabrication of biosensors.…”

Rational Atomic Engineering of Prussian Blue Analogues as Peroxidase Mimetics for Colorimetric Urinalysis of Uric Acid

“…Enzyme mimetics have been exploited as alternatives for natural enzymes for decades, among which nanosized materials with intrinsic enzyme-like activities (later coined as nanozymes) are most promising and widely studied owing to their unique advantages including stable structures, modulated activities, low costs, and large-scale preparation. , After years of productive research, albeit with different voices from the academia, many types of nanozymes were developed with activities close to and even defeating their natural counterparts, such as horseradish peroxidase, catalase, oxidase, and superoxide dismutase, among which peroxidase mimetics were extensively studied because of their promising applications as catalytic labels in the fabrication of POCT devices. − Prussian blue (PB) is one interesting nanozyme that attracts attention dating back to the year 2000 when it was used as an electrochemical transducer for H 2 O 2 by which it was denoted as “artificial peroxidase”, but it was after 16 years that the facets of multienzyme mimetics of PB were proposed and investigated deeply . Followed by this, very recently, a paper-based colorimetric glucose sensor was proposed using PB nanoparticles (NPs) as mimic peroxidase . Besides PB, their cyanometallate structural analogues also exhibited different peroxidase-like activities dictated by the specific chemical reaction, , leaving behind two questions that (1) how the catalyzed oxidation of TMB by H 2 O 2 works in the presence of PB and its analogues and (2) particularly how the species and doping ratio of metal elements affect the peroxidase-like activity.…”

“…26 Followed by this, very recently, a paperbased colorimetric glucose sensor was proposed using PB nanoparticles (NPs) as mimic peroxidase. 27 Besides PB, their cyanometallate structural analogues also exhibited different peroxidase-like activities dictated by the specific chemical reaction, 28,29 leaving behind two questions that (1) how the catalyzed oxidation of TMB by H 2 O 2 works in the presence of PB and its analogues and (2) particularly how the species and doping ratio of metal elements affect the peroxidase-like activity.…”