Paper-based electrochemiluminescence determination of streptavidin using reticular DNA-functionalized PtCu nanoframes and analyte-triggered DNA walker

Huang, Yuzhen; Zhang, Lina; Si-bao, Zhang; Zhao, Peini; Li, Li; Ge, Shenguang; Yu, Jinghua

doi:10.1007/s00604-020-04515-0

Cited by 8 publications

(5 citation statements)

References 31 publications

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“…Sun has developed a rotating μPad for multi-step ECL immunoassay of CEA and Prostate specific antigen (PSA) with the advantages of reusable rotary valve and short response time [ 87 ]. In addition, based on the DNA Walker's strand displacement reaction and the catalysis of DNA-Pt/CuTNFs [ 88 ], an enhanced luminol ECL signal was obtained to detect streptavidin with a low detection limit of 33.4 fmol/L (Fig. 2 c).…”

Section: Electrochemical Detection Methodsmentioning

confidence: 99%

“…2 Some examples for ECL detection. a Paper-based ECL device for MCF-7 detection [ 84 ]; b Schematic illustration for paper-based ECL device for Ni 2+ and Hg 2+ detection [ 86 ]; c Principle for paper-based ECL device of the analyte-triggered DNA walker [ 88 ] …”

Section: Electrochemical Detection Methodsmentioning

confidence: 99%

“…For example, Gong's team [116] developed a microfluidic platform that collected human serum by a pulling-force spinning top (PFST) and paper-based microfluidic enzyme-linked immunosorbent assay (ELISA) for quantity of IgA/IgM/ IgG in an instrument-free way. It can easily isolate the [86]; c Principle for paper-based ECL device of the analyte-triggered DNA walker [88] serum without any clinical apparatus, and a portable smart phone made it easy to record the intensity signal. Moreover, in 2020, Li's group [117] presented a microfluidic system that can centrifugate human whole blood and quantify carcinoembryonic antigen and alpha fetoprotein by ELISA method with LODs of 360 pg/mL and 280 pg/mL for CEA and AFP, respectively.…”

Section: Biochemical Analysismentioning

confidence: 99%

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Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

Hou

Guo

et al. 2022

J. Anal. Test.

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Point-of-care testing (POCT), as a portable and user-friendly technology, can obtain accurate test results immediately at the sampling point. Nowadays, microfluidic paper-based analysis devices (μPads) have attracted the eye of the public and accelerated the development of POCT. A variety of detection methods are combined with μPads to realize precise, rapid and sensitive POCT. This article mainly introduced the development of electrochemistry and optical detection methods on μPads for POCT and their applications on disease analysis, environmental monitoring and food control in the past 5 years. Finally, the challenges and future development prospects of μPads for POCT were discussed.

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Section: Electrochemical Detection Methodsmentioning

confidence: 99%

Section: Electrochemical Detection Methodsmentioning

confidence: 99%

Section: Biochemical Analysismentioning

confidence: 99%

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Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

Hou

Guo

et al. 2022

J. Anal. Test.

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“…Conventionally, polymerase chain reaction (PCR) is the technique extensively used to rapidly process millions to billions of DNA samples, but it requires precise temperature control for reactions, and hence, to date has been unsuccessfully applied to PADs [ 149 , 150 ]. Alternatively, various signal amplification isothermal methods have been tried for PAD development, including rolling circle amplification (RCA) [ 147 , 151 , 152 , 153 , 154 , 155 ], loop-mediated isothermal amplification (LAMP) [ 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 165 , 166 ], strand-displacement amplification (SDA) [ 167 ], recombinase polymerase amplification (RPA) [ 168 , 169 , 170 , 171 ], helicase dependent amplification (HDA) [ 172 , 173 , 174 ], and nucleic acid sequence-based amplification (NASBA) [ 175 ].…”

Section: Nucleic Acid-mediated Signal Amplificationmentioning

confidence: 99%

Advanced Signal-Amplification Strategies for Paper-Based Analytical Devices: A Comprehensive Review

Hoang

Phan

et al. 2021

Biomedicines

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Paper-based analytical devices (PADs) have emerged as a promising approach to point-of-care (POC) detection applications in biomedical and clinical diagnosis owing to their advantages, including cost-effectiveness, ease of use, and rapid responses as well as for being equipment-free, disposable, and user-friendly. However, the overall sensitivity of PADs still remains weak, posing a challenge for biosensing scientists exploiting them in clinical applications. This review comprehensively summarizes the current applicable potential of PADs, focusing on total signal-amplification strategies that have been applied widely in PADs involving colorimetry, luminescence, surface-enhanced Raman scattering, photoacoustic, photothermal, and photoelectrochemical methods as well as nucleic acid-mediated PAD modifications. The advances in signal-amplification strategies in terms of signal-enhancing principles, sensitivity, and time reactions are discussed in detail to provide an overview of these approaches to using PADs in biosensing applications. Furthermore, a comparison of these methods summarizes the potential for scientists to develop superior PADs. This review serves as a useful inside look at the current progress and prospective directions in using PADs for clinical diagnostics and provides a better source of reference for further investigations, as well as innovations, in the POC diagnostics field.

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“…Unlike the complex mechanisms behind it, the technique itself is fairly easy to employ and quantify. Various ECL systems have been studied since its discovery for the detection of analytes including luminol, [19][20][21] [Ru(bpy) 3 ] 2 + , [22][23][24] QDs, [15,[25][26][27] etc. Among these systems, the ECL of luminol in a hydrogen peroxide system seems more promising as the intensity of the electrochemicallygenerated light of the luminophore can be directly related to the concentration of H 2 O 2 leading to accurate quantification of the analyte.…”

Section: Introductionmentioning

confidence: 99%

Ti₃C₂/Ni/Sm‐Based Screen‐Printed‐Electrode for the ECL Detection of Hydrogen Peroxide as a Milk Preservative

Arshian,

Firoozbakhtian,

Salehnia

et al. 2024

ChemistrySelect

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Hydrogen peroxide is a widely used agent in the food industry for its sterilization, packaging, and transportation capabilities. However, its excessive concentration can lead to adverse health effects, especially in gastrointestinal conditions. As a result, it is crucial to detect its presence in food products, particularly milk. To address this need, we have developed a state‐of‐the‐art MXene‐based ECL system that can detect low‐concentration hydrogen peroxide levels with high sensitivity and accuracy. Our system incorporates 2D MXene structures, which not only enhance electrode conductivity but also form a complex with Ni/Sm‐LDH (layered double hydroxide) that enables detection across a broad linear range of 0.05–2 ppm in real samples. Furthermore, we have successfully lowered the detection limit to an impressive 0.005 ppm. With this innovative approach, we can ensure the safety and quality of food products, making it a significant breakthrough in the food industry.

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Paper-based electrochemiluminescence determination of streptavidin using reticular DNA-functionalized PtCu nanoframes and analyte-triggered DNA walker

Cited by 8 publications

References 31 publications

Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

Advanced Signal-Amplification Strategies for Paper-Based Analytical Devices: A Comprehensive Review

Ti₃C₂/Ni/Sm‐Based Screen‐Printed‐Electrode for the ECL Detection of Hydrogen Peroxide as a Milk Preservative

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Paper-based electrochemiluminescence determination of streptavidin using reticular DNA-functionalized PtCu nanoframes and analyte-triggered DNA walker

Cited by 8 publications

References 31 publications

Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

Recent Advances and Applications in Paper-Based Devices for Point-of-Care Testing

Advanced Signal-Amplification Strategies for Paper-Based Analytical Devices: A Comprehensive Review

Ti3C2/Ni/Sm‐Based Screen‐Printed‐Electrode for the ECL Detection of Hydrogen Peroxide as a Milk Preservative

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Product

Resources

About

Ti₃C₂/Ni/Sm‐Based Screen‐Printed‐Electrode for the ECL Detection of Hydrogen Peroxide as a Milk Preservative