Paper-based electrochemiluminescence origami cyto-device for multiple cancer cells detection using porous AuPd alloy as catalytically promoted nanolabels

Wu, Ludan; Ma, Chao; Ge, Lei; Kong, Qingkun; Yan, Mei; Ge, Shenguang; Yu, Jinghua

doi:10.1016/j.bios.2014.07.077

Cited by 83 publications

(54 citation statements)

References 45 publications

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“…[48] They noted that this was the first report of ECL-based cyto-sensing on a paper-based analytical device. This device was constructed similarly to the one previously discussed, except that it had an array of four screen printed carbon working electrodes.…”

Section: D Origami Microfluidic Devicesmentioning

confidence: 99%

“…[42] Folding precluded tricky alignment procedures and exact cutting. These initial devices utilized fluorescence and colorimetric detection, but electrochemical [43] and ECL-based microfluidic devices [44][45][46][47][48][49] and paper chips [50] were soon reported. Yu's group has fabricated a 3D microfluidic device that simultaneously detected two species, Pb 2 + and Hg 2 + .…”

Section: D Origami Microfluidic Devicesmentioning

confidence: 99%

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Electrochemiluminescence Detection in Paper‐Based and Other Inexpensive Microfluidic Devices

et al. 2017

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There is a need in the field of microfluidics for integration of analytical detection methods onto small fluidic chips. Electrogenerated chemiluminescence (ECL) is an effective method for detecting a wide range of analytes, including small molecules, metal ions and bacteria. This Minireview discusses recent applications of ECL-based detection methods to inexpensive microfluidic devices. We discuss various paper and cloth based devices, including 3D-origami devices and devices utilizing bipolar electrodes. We also discuss novel devices that have replaced traditional instrumentation with inexpensive and portable equipment, such as mobile phones.

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Section: D Origami Microfluidic Devicesmentioning

confidence: 99%

Section: D Origami Microfluidic Devicesmentioning

confidence: 99%

Electrochemiluminescence Detection in Paper‐Based and Other Inexpensive Microfluidic Devices

et al. 2017

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“…54 In another report that aimed to detect multiple cancer cells, AuNPs were conjugated to palladium and concanavalin-A bioconjugates in order to improve detection. 55 In order to detect acetaminophen in the presence of ascorbic acid, conjugation of AuNPs to polyglutamic acid and single wall carbon nanotubes was implemented by Lee and colleagues. 27 Wang and colleagues reported the immobilisation of AuNPs with silver in order to increase the resistance for detection of carcinoma antigen 125 (CA 125).…”

Section: ·4 Electrodes Characterization: Fabrication and Surface Modmentioning

confidence: 99%

Trends in Paper-based Electrochemical Biosensors: From Design to Application

et al. 2018

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Electrochemical bio-sensing using paper-based detection systems is the main focus of this review. The different existing designs of 2-dimensional and 3-dimensional sensors, and fabrication techniques are discussed. This review highlights the effect of adopting different sensor designs, distinct fabrication techniques, as well as different modification methods, in order to produce reliable and reproducible reading. The use of various nanomaterials have been demonstrated in order to modify the surface of electrodes during fabrication to further enhance the signal for subsequent analysis. The reviewed sensors were classified into categories based on their applications, such as diagnostics, environmental and food testing. One of the major advantages of using paper-based electrochemical sensors is the potential for miniaturization, which only requires relatively small amount of samples, and the low cost for the purpose of mass production. Additionally, most of the devices reviewed were made to be portable, making them well-suited for on-site detection. Finally, paper-based detection is an ideal platform to fabricate cost-effective, user-friendly and sensitive electrochemical biosensors, with large capacity for customization depending on functional needs.

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“…Of these, electrochemical techniques provide a unique characteristic of being exceptionally sensitive, considerably fast, and highly cost effective. To date, various electrochemical methods have been developed for the detection of cancer using the expression of the surface proteins as biomarkers (Chandra et al, 2013;Zhu et al, 2012;Lee et al, 2015;Han et al, 2014;Wu et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Enhanced electrochemical sensing of leukemia cells using drug/lipid co-immobilized on the conducting polymer layer

Gurudatt

Naveen

Ban

et al. 2016

Biosensors and Bioelectronics

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Paper-based electrochemiluminescence origami cyto-device for multiple cancer cells detection using porous AuPd alloy as catalytically promoted nanolabels

Cited by 83 publications

References 45 publications

Electrochemiluminescence Detection in Paper‐Based and Other Inexpensive Microfluidic Devices

Electrochemiluminescence Detection in Paper‐Based and Other Inexpensive Microfluidic Devices

Trends in Paper-based Electrochemical Biosensors: From Design to Application

Enhanced electrochemical sensing of leukemia cells using drug/lipid co-immobilized on the conducting polymer layer

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