Paper Patching Versus Watchful Waiting of Traumatic Tympanic Membrane Perforations: A <scp>Meta‐Analysis</scp>

Simani, Liam; Oron, Yahav; Handzel, Ophir; Eta, Rani Abu; Warshavsky, Anton; Horowitz, Gilad; Muhanna, Nidal; Ungar, Omer J.

doi:10.1002/lary.29580

Cited by 12 publications

(2 citation statements)

References 33 publications

(140 reference statements)

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“…Third, recent studies including meta-analysis showed that the recovery rate of TTMP in the paper patching group was statistically higher than that in the observation group. 22 , 23 Therefore, it may lower the necessity of future surgical treatment for tympanic membrane perforation compared to the watchful observation.…”

Section: Discussionmentioning

confidence: 99%

Human Acellular Dermal Allograft Patch on Traumatic Tympanic Membrane Perforation

Lee¹,

Yeo²,

Kim³

2022

Int Adv Otol

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Background: This study aimed to investigate the outcome of using the human acellular dermal allograft patch compared with the conventional paper patch in traumatic tympanic membrane perforation. Methods: This was a retrospective study including 41 patients (42 ears) treated with 22 human acellular dermal allografts and 20 paper patches for acute traumatic tympanic membrane perforation from April 2013 to June 2020. The procedure was performed by applying human acellular dermal allograft or paper patches after trimming of perforation margins under local anesthesia. Patient’s age, sex, cause, duration, side, location, size of perforation, and the result of healing was analyzed. The audiologic or computed tomography data were also investigated when available. Results: There was no significant difference in sex, age, affected side ratio, size and duration of perforation, recovery confirmation time, and audiogram results between the two groups. There was no significant difference in the size or duration of perforation between the success and failure groups. The human acellular dermal allograft and paper-patch groups showed no significant difference in the recovery confirmation time (70.7 ± 42.3 vs. 89.9 ± 119.4 days, P = .486) and recovery rate (95.5% vs. 85.0%, P = .333). However, the patch maintenance time of the human acellular dermal allograft group was statistically longer than the paper-patch group (32.9 ± 14.9 vs. 15.6 ± 19.9 days, P = .001). On multivariable regression analysis, patch material was the only parameter associated with patch maintenance time ( P = .002). Conclusion: Treatment outcomes of traumatic tympanic membrane perforation using human acellular dermal allograft showed better or similar therapeutic efficacy compared to paper patch. The important advantage of this material is to stay in situ for a sufficient time without being detached until successful healing.

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Section: Discussionmentioning

confidence: 99%

Human Acellular Dermal Allograft Patch on Traumatic Tympanic Membrane Perforation

Lee¹,

Yeo²,

Kim³

2022

Int Adv Otol

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“…After the enrolment process was completed, a manual review of all the references cited in the enrolled studies was performed in search of additional articles for inclusion. This process was performed to allow studies that had not been identified according to our keyword search to be identified and assessed for suitability for inclusion; this method having been demonstrated as being efficient for additional article inclusion in otolaryngology (20)(21)(22). A quantitative data sheet was constructed, and each relevant publication was analyzed in terms of demographic data and affected cranial and spinal nerves.…”

Section: Data Extraction and Quality Assessmentmentioning

confidence: 99%

The Significance of Bell's Palsy That Presents as Monocranial Versus Polycranial Neuropathy: A Case Series and Systematic Literature Review

Ziv,

Hazout,

Goldberg

et al. 2023

Otol Neurotol

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Purpose To investigate the effect of Bell's palsy (BP) presenting as polycranial neuropathy (PCN) compared with BP caused by isolated facial nerve (CNVII). Methods We carried out a retrospective cohort study of the medical records of all consecutive patients who were diagnosed with BP at a single tertiary referral center between 2010 and 2017. Included were patients 18 years or older who were clinically diagnosed with BP and completed 7 days of systemic steroidal treatment and at least 6 months of follow-up. The patients were divided into two groups according to whether the BP derived from a monocranial neuropathy or a PCN. Demographics and BP severity and outcome were compared between these groups. A systematic literature review using Medline via “PubMed,” “Embase,” and “Web of Science” was conducted. Results In total, 321 patients with BP were enrolled. The median (interquartile range) age at presentation was 44 (33–60) years. Sex distribution showed male predominance of 57.6% (n = 185) versus 42.4% (n = 136), and 21.2% (n = 68) had PCN. The most concomitantly affected cranial nerve (CN) was the trigeminal (CNV; n = 32, 47%), followed by the glossopharyngeal nerve (CNIX; n = 14, 21%) and the audiovestibular nerve (CNVIII; n = 10, 15%). Age, House-Brackmann score on presentation, and diabetes mellitus (DM) were independent predictors for PCN etiology (p = 0.001, p = 0.034, and p < 0.001, respectively). Each increase in 1 year of age was associated with additional odds ratio (95% confidence interval) of 0.97 (0.95–0.99) for PCN. The odds ratio (95% confidence interval) associated with DM was 8.19 (4.02–16.70). Our systematic literature review identified 1,440 patients with the PCN type of BP. The most commonly affected CN was the trigeminus (25–48%), followed by the glossopharyngeal and audiovestibular nerves (2–19% and 0–43%, respectively). Conclusion The severity of facial weakness on initial presentation among PCN patients was significantly higher compared with the monocranial neuropathy–type BP patients. The authors believe that the significant association and prevalence rate ratio between DM and PCN warrant that a patient presenting with PCN undergo screening for DM.

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Äußeres Ohr, Gehörgang, Mittelohr (ohne Hörstörungen), Felsenbein

Michel

2023

Gutachten in Der HNO

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Paper Patching Versus Watchful Waiting of Traumatic Tympanic Membrane Perforations: A Meta‐Analysis

Cited by 12 publications

References 33 publications

Human Acellular Dermal Allograft Patch on Traumatic Tympanic Membrane Perforation

Human Acellular Dermal Allograft Patch on Traumatic Tympanic Membrane Perforation

The Significance of Bell's Palsy That Presents as Monocranial Versus Polycranial Neuropathy: A Case Series and Systematic Literature Review

Äußeres Ohr, Gehörgang, Mittelohr (ohne Hörstörungen), Felsenbein

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