Papillary carcinoma in a thyroglossal cyst: report of a case and review of literature

Thakar, A.; Tandon, D. A.; Sharma, Shantanu

doi:10.1007/bf03022727

Cited by 4 publications

(4 citation statements)

References 6 publications

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“…Ninety‐eight articles met the inclusion criteria and were included in the final analysis with a total population of 164 patients. Eighty‐one case reports and 17 case series were included 4–101 . The largest case series included 18 patients, and the studies that we evaluated spanned from 1986 to 2016.…”

Section: Resultsmentioning

confidence: 99%

Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Features and Outcomes

Rayess

Monk

Svider

et al. 2017

Otolaryngol.--head neck surg.

115

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Objective Although thyroglossal duct cysts (TGDCs) are relatively common, malignancies within these lesions are infrequent. As a result, there are no large-scale series describing clinical characteristics. Our objectives were to perform a systematic review of the literature evaluating patient demographics, pathology, management, and prognosis of these patients. Data Sources PubMed, Embase, Cochrane reviews, and Google Scholar were searched for relevant articles. Articles meeting inclusion criteria were reviewed for data detailing epidemiology, treatment, and outcomes. Review Methods Inclusion criteria included English-language articles with original reports on human subjects. Two investigators independently reviewed all articles for the data collected, including epidemiology, treatment, and outcomes. Results Ninety-eight articles comprising 164 patients were included in the final analysis. The mean age at presentation was 39.5 years (9-83 years); 68.3% of patients were female. In total, 73.3% of cases were found on final pathologic analysis. The most common pathology was papillary cancer (92.1%). Of the patients, 98.9% underwent a Sistrunk procedure and 61.0% underwent total thyroidectomy. There was a 4.3% recurrence rate with a mean time to recurrence of 42.1 months from initial treatment. One patient died of TGDC carcinoma, while all other patients were disease free at the time of last follow-up (mean follow-up was 46.1 months). Conclusion TGDC carcinoma is typically diagnosed on final pathology. While management encompasses a Sistrunk procedure, further consideration should be given to thyroidectomy among patients ≥45 years of age and individuals with aggressive disease. TGDC carcinoma harbors an exceedingly low rate of mortality.

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Section: Resultsmentioning

confidence: 99%

Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Features and Outcomes

Rayess

Monk

Svider

et al. 2017

Otolaryngol.--head neck surg.

115

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“…All the patients must have a six-month follow-up in the first year and there after annually. 27 Follow-up should include thorough physical examination, ultrasound of the surgical site and thyroid gland and thyroid scan. 28…”

Section: Pathological Discussionmentioning

confidence: 99%

Papillary Carcinoma Thyroid in Thyroglossal Cyst- A Case Report

Rao¹,

Rao²,

Kumar³

et al. 2019

jebmh

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“…The risk of metastasis is less than 2% of cases [ 6 ]. Careful long-term follow-up is important as papillary carcinoma is usually a low-grade malignancy and recurrences can be successfully treated with careful patient follow-up [ 29 ]. All patients must have a neck scan and be re-assessed every six months during the first year and annually after that [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

Invasive Thyroglossal Duct Cyst Papillary Carcinoma: A Case Report and Review of the Literature

et al. 2018

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Patient: Female, 27Final Diagnosis: Invasive thyroglossal duct cyst papillary carcinomaSymptoms: Painless cervical enlargementMedication: —Clinical Procedure: Sistrunk’s procedureSpecialty: SurgeryObjective:Rare diseaseBackground:Thyroglossal duct cyst is a common congenital anomaly of the thyroid gland, usually found centrally. The presence of malignancy occurring in a thyroglossal duct cyst is a rare condition, accounting only for 1% of all cases of thyroglossal duct cyst. This report is of a rare case of papillary carcinoma arising in a thyroglossal duct cyst and includes a review of the literature.Case Report:A 27-year-old female patient was referred to our department with a painless cystic mass in the neck. After initial physical examination and endocrinology investigations, a fine needle aspiration (FNA) of the cyst was performed. Cytology showed a papillary neoplasm. The patient underwent total thyroidectomy and surgical excision of the thyroglossal duct cyst (the Sistrunk’s procedure). Histopathology of the surgical excision specimen showed a thyroglossal duct cyst with a maximum diameter of 7.5 cm containing a primary invasive papillary carcinoma, measuring 1.5 cm in diameter that infiltrated into the cyst wall. The remaining thyroid gland was normal.Conclusions:Thyroglossal duct carcinoma, most commonly papillary carcinoma, is a rare condition that should be considered in patients presenting with cystic midline neck masses. Surgery and complete excision is the main treatment and the optimal patient management includes multidisciplinary consultation in order to improve survival. The diagnosis of malignancy is made postoperatively, as in the present case.

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Papillary carcinoma in a thyroglossal cyst: report of a case and review of literature

Abstract: Abstract

Cited by 4 publications

References 6 publications

Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Features and Outcomes

Thyroglossal Duct Cyst Carcinoma: A Systematic Review of Clinical Features and Outcomes

Papillary Carcinoma Thyroid in Thyroglossal Cyst- A Case Report

Invasive Thyroglossal Duct Cyst Papillary Carcinoma: A Case Report and Review of the Literature

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