Papillary thyroid carcinoma and laryngeal squamous cell carcinoma manifesting as a collision tumor of the neck: A case report

Abstract

A 55-year-old male presented with a rapidly expanding mass on the right side of the neck and progressive hoarseness. An electronic laryngoscopy and a computed tomography scan were performed, and the patient was subsequently diagnosed with tumors of the larynx and the thyroid gland. An en bloc near-total thyroidectomy combined with a total laryngectomy was performed. The final pathological analysis revealed a collision tumor that was derived from a laryngeal squamous cell carcinoma and a papillary thyroid carcinoma. Collision tumors of the head and neck are rare. The therapy for a collision tumor should consist of a combination of the treatments that are normally used for each focus.

Four-Cell Population Collision Tumor of the Scalp: A Case Report and Review of Literature

“…Five reviewed articles documented recurrent distal metastasis within 3 to 12 months after initial treatment. [15][16][17][18][19] Lymph node infiltration did not suggest any correlation with distal metastasis following treatment. There were reported deaths for 3 of those patients.…”

Oral collision cancer: A case report and literature review of simultaneous squamous cell and adenoid cystic carcinoma of the oral mucosa

“…1,2 Collision carcinomas have been described in various organs including the cranium, lungs, stomach, larynx, and thyroid gland [3][4][5][6][7] with several cases reported in the head and neck but very rarely in the oral mucosa (Table 1). [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] Indeed, and to the best of our knowledge, only two cases of oral collision cancer have been reported (Table 1: Cases 1 and 4). More specifically, Takeda et al 8 describe a collision between duct carcinoma and SqCC in the lip, while Falanga et al 11 report a collision cancer between desmoplastic melanoma and SqCC occurring in the mouth floor.…”

Thyroid collision tumor containing oncocytic carcinoma, classical and hobnail variants of papillary carcinoma and areas of poorly differentiated carcinoma

“…Collision tumors, defined as two or more neoplasms coexisting in one anatomical site with distinct histology, are rare (16). Thyroid collision tumors are rare, and just over 40 case reports have been described (16)(17)(18)(19)(20)(21)(22)(23).…”