Papillary tumor of the pineal region in pediatric patient – A case report

Abstract

Background: Papillary tumor of the pineal region (PTPR) represents a rare and histologically distinct subgroup of tumors originating in the pineal region. Few pediatric cases have been reported so far in the literature; therefore, clinical data are scarce. Case Description: We describe a case of PTPR in a 9-year-old girl who presented with a 5-month history of excessive appetite and weight gain. The patient underwent neuroimaging procedures and total gross surgical resection with postoperative adjuvant local radiotherapy, which from our experience was the best treatment choice as an attempt to avoid local recurrence. During 78-month follow-up, the patient from our study manifested no disease recurrence. Conclusion: PTPR should be included in the differential diagnosis of pineal region masses.

Pediatric diencephalic tumors: a constellation of entities and management modalities

“…The reported age range of this tumor is between 1 and 71 years. In the pediatric population, the median age of presentation is approximately 11.6 years, with a slight female predilection (115)(116)(117)(118). This entity was first described in 2003 and subsequently enlisted in the WHO classification of CNS tumors in 2007 as Grade 2 or 3 lesions (115).…”

“…Imaging: On imaging, these tumors are heterogeneously enhancing, mixed solid and cystic masses that often obstruct the cerebral aqueduct, causing secondary hydrocephalus. Intrinsic T1 hyperintense proteinaceous secretions are also occasionally seen (115)(116)(117)(118).…”