Paradoxical neutrophilic dermatosis induced by biologics and immunosuppressive drugs: A systematic review

Haber, Richard M.; Dib, Nicole; Gemayel, Maria El; Makhlouf, Milissa

doi:10.1016/j.jaad.2021.02.035

Cited by 4 publications

(1 citation statement)

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“…9 Although the exact immunological pathogenesis remains unknown, it is possible that the inhibition of speci c pathways paradoxically leads to the development of neutrophilic dermatoses, such as Sweet's syndrome, as a side e ect of psoriasis treatment. 10 Saeed et al reported the case of a patient with a history of psoriasis who presented with tender erythematous plaques with a hemorrhagic crust and bullae, leading to the diagnosis of Sweet's syndrome. 8 Additionally, this patient had blood test ndings suggestive of Hashimoto's thyroiditis that improved with steroid treatment.…”

Section: Case Reportmentioning

confidence: 99%

A Case of Psoriasis Concomitant with Sweet’s Syndrome

Kim,

Lee

2023

JKSP

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Psoriasis often coexists with other skin conditions, which adds to the complexity of patient management. Sweet's syndrome, a rare inflammatory skin disorder, is rarely associated with psoriasis, and its etiology remains elusive. Herein, we present a unique case of Sweet's syndrome in a patient with psoriasis. A 46-year-old man, with a history of psoriasis-like skin lesions treated with an unidentified medication, developed painful erythematous plaques and fever. He was diagnosed with Sweet's syndrome after a skin biopsy. Steroid therapy initially improved the patient's symptoms; however, its discontinuation led to the recurrence of psoriasis-like scaly plaques. An additional skin biopsy confirmed the diagnosis of psoriasis. Complete resolution of the lesions was achieved after 7 months of methotrexate treatment. In conclusion, this is the first reported case of psoriasis concomitant with Sweet's syndrome in Korea, highlighting the importance of recognizing coexisting skin conditions in patients with psoriasis despite their rarity.

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Section: Case Reportmentioning

confidence: 99%