Paragangliomas of the lumbar region

Gelabert-González, Miguel

doi:10.3171/spi.2005.2.3.0354

Cited by 58 publications

(43 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…El diagnóstico diferencial debe hacerse con otros tumores de la misma localización, como astrocitomas, paragangliomas del filum 13 , schwannomas 4,6 , epidermoides, etc. El tratamiento microquirúrgico es el de elección en los tumores de esta localización.…”

Section: Discussionunclassified

Ependimomas del filum terminal. Análisis de 20 casos consecutivos

et al. 2010

View full text Add to dashboard Cite

ResumenObjetivos. Analizar las características clínicas, radiológicas y los resultados quirúrgicos de una serie de ependimomas del filum terminal.Pacientes y método. Se estudia retrospectivamente 20 pacientes con 21 ependimomas del filum terminal tratados durante un período de 21 años . Todos los pacientes fueron diagnosticados con resonancia magnética e intervenidos quirúrgicamente.Resultados. La relación varón-mujer fue de 1:1.5 y la media de edad al diagnóstico de 44.8 años (rango 15-64). El primer síntoma fue dolor radicular (12 casos) y lumbalgia en los 8 restantes, con una duración media de la sintomatología antes del diagnostico de 8.7 años (rango 0.6-32). Todos los pacientes fueron intervenidos quirúrgicamente realizándose resección completa de 17 tumores y subtotal de 4. Histológicamente 20 tumores fueron ependimomas mixopapilares (grado I ) y un caso grado II. El período de seguimiento fue de 8 años (rango 1-18).Conclusiones. Los ependimomas del filum terminal, son tumores de crecimiento lento con una mayor incidencia en adultos jóvenes. La forma de presentación más habitual es con dolor lumbar con un largo tiempo de evolución. Aunque la mayoría son tumores de bajo grado histológico, tienen una especial tendencia a crecer y las recidivas locales no son raras.PALABRAS CLAVE: Ependimoma. Filum terminal. Resonancia magnética. Tumor medular. Tumor mixopapilar. Conclusions. Filum terminale ependimomas are slow growing tumours of the cauda equina with a high incidence in young adults. The most common presentation is with low back pain long time evolution. Although ependymomas of the filum terminale are thought to be benign, local recurrence is not uncommon.KEY WORDS: Ependymoma. Filum terminale. Magnetic resonance imaging. Myxopapillary tumor. Spinal cord tumor, IntroducciónLos ependimomas medulares son tumores poco frecuentes que constituyen menos del 5% de todos los tumores del sistema nervioso central (SNC) y entre el 10-15% de todos los tumores espinales 14,19 . Los ependimomas de la región lumbo-sacra representan el 30% de todos los ependimomas espinales y se trata habitualmente de ependimomas mixopapilares, variedad descrita por Kernohan en 1932 16 y que de acuerdo con la clasificación de la organización mundial de la salud (OMS) son tumores grado I. Clínicamente se caracterizan por presentarse con dolor lumbar con o sin irradiación ciática, por lo que se confun-

show abstract

Section: Discussionunclassified

Ependimomas del filum terminal. Análisis de 20 casos consecutivos

et al. 2010

View full text Add to dashboard Cite

show abstract

“…[5] In the CNS, the most common extra spinal localizations of PG are the petrous ridge, pineal gland and sella turcica. [5678] The first published, although unrecognized case of a cauda equina region PG dates back to 1970. [6] This study describes the clinicopathological features of eight cases of PG of the spinal canal.…”

Section: Introductionmentioning

confidence: 99%

Primary paraganglioma of the spine: A clinicopathological study of eight cases

Mishra

Goel

2014

J Craniovert Jun Spine

View full text Add to dashboard Cite

Context:Spinal paragangliomas are rare neuroendocrine tumors of the extra-adrenal paraganglionic system.Aims:This study describes the clinicopathological features of eight cases of spinal paraganglioma and highlights the significance of important morphological features and immunohistochemistry in the diagnosis of paraganglioma at this unusual site.Material and Methods:All the cases of primary spinal paragangliomas diagnosed during the last six years (2008-2013) in the Department of Pathology at our hospital were reviewed.Results:There were six males and two females. The mean age at diagnosis was 50.4 years. All patients presented with low back pain. All tumors were located in the cauda equina or conus medullaris region. Magnetic Resonance Imaging and intraoperative appearance were that of a vascular, well-circumscribed intradural, extramedullary tumor suggestive of either schwannoma or ependymoma. All the patients underwent gross total resection of the tumor. Histopathology in five of the cases showed ‘ependymoma-like histology’ while only three cases had a predominant classic ‘zellballen’ pattern. Two cases had prominent ‘gangliocytic differentiation’. In the five cases with ‘ependymoma-like histology’, the diagnosis was confirmed on Immunohistochemistry (IHC).Conclusions:Even though relatively rare, paraganglioma should be considered in the differential diagnosis of spinal tumors and due to their clinical, radiological and histopathological similarity to schwannoma and ependymoma, the diagnosis should be based on close examination of the clinical, radiological and pathological findings.

show abstract

“…Spinal involvement is uncommon; a vast majority of these tumors are intradural and found within the cauda equina [3,5,6,7,8,9]. Extradural paragangliomas involving the spine occur rarely, and only few cases involving the thoracolumbar region have been reported previously [10,11,12,13,14].…”

Section: Discussionmentioning

confidence: 99%

“…The most common sites of origin of paragangliomas are the carotid body and glomus jugulare; the tumors arising from the rest of the paraganglion system are uncommon [3, 4]. Paragangliomas involving the spinal canal are rare and mainly take the form of intradural compression of the cauda equina [3,5,6,7,8,9] or intra-/extradural compression of the thoracic cord [10,11,12,13,14]. Primary paraganglioma involving the cervical spine is very rare and only few cases have been previously reported [15,16,17,18].…”

Section: Introductionmentioning

confidence: 99%

Dumbbell-Shaped Paraganglioma of the Cervical Spine in a Child

Ojha¹,

Sharma²,

Rastogi³

et al. 2006

Pediatr Neurosurg

View full text Add to dashboard Cite

Paragangliomas are tumors arising from extra-adrenal paraganglia and account for 0.3% of all neoplasms. The carotid body and temporal bone are the most frequent sites of paraganglioma, though it has been reported to occur in almost every part of the body. Spinal paragangliomas are uncommon and mainly take the form of intradural compression of the cauda equina or thoracic cord. Extradural paragangliomas are still rare; only few cases involving the dorsolumbar spine have been reported. We are reporting an interesting case of a dumbbell-shaped primary extradural paraganglioma of the cervical spine in an 8-year-old boy that presented with progressively increasing spastic quadriparesis.

show abstract

Paragangliomas of the lumbar region

Abstract: ✓ The author reports two cases of cauda equina paraganglioma (CEP) and provides a review of all previously published cases. The current radiological, neurosurgical, and pathological literature on this rare tumor is also reviewed.

Cited by 58 publications

References 74 publications

Ependimomas del filum terminal. Análisis de 20 casos consecutivos

Ependimomas del filum terminal. Análisis de 20 casos consecutivos

Primary paraganglioma of the spine: A clinicopathological study of eight cases

Dumbbell-Shaped Paraganglioma of the Cervical Spine in a Child

Contact Info

Product

Resources

About