Arrays of individual atoms trapped in optical microtraps with micrometer‐scale sizes have emerged as a fundamental, versatile, and powerful platform for quantum sciences and technologies. This platform enables the bottom‐up engineering of quantum systems, offering the capability of low‐entropy preparation of quantum states with flexible geometry, as well as manipulation and detection at the single‐site level. The utilization of ultracold itinerant atoms with tunnel coupling in optical microtraps provides new opportunities for quantum simulation, enabling the exploration of exotic quantum states, phases, and dynamics, which would otherwise be challenging to achieve in conventional optical lattices due to high entropy and limited geometric flexibility. Here, the development of tunnel‐coupled optical microtraps for the manipulation of ultracold atomic quantum systems and its recent advances are briefly reviewed.