Abstract-As the fabrication of prototypes is very costly, system-level computer simulations have become commonplace alternatives for the design of electronic devices and systems. However, due to the computational cost of these simulations, the use of behavioral modeling techniques has become indispensable. Behavioral models can act as a surrogate for the expensive simulations, and effectively speed-up the simulations without sacrificing accuracy. Such models are compact and cheap to evaluate, and have proven very useful for tasks such as optimization, design space exploration, prototyping, and sensitivity analysis. Consequently, there is great interest in techniques that facilitate the construction of behavioral models, while minimizing the computational cost and maximizing model accuracy. This paper explores how such models can be calculated in an automated way by means of a unified software framework that integrates adaptive modeling and adaptive sampling methods. It generates global behavioral models that are accurate and valid over the design space of interest while minimizing the number of electromagnetic simulations. By placing a strong focus on adaptivity, flexibility, and self-tuning the burden on the designer is relieved and the total modeling turn-around time is reduced.