The parallel and distributed simulation field has evolved and grown from its origins in the 1970s and 1980s and remains an active field of research to this day. A brief overview of research in the field is presented. Future research topics are explored including areas such as problem-driven simulation of large-scale systems and complex networks, exploitation of graphical processing unit hardware and cloud computing environments, predictive online simulation for system management and optimization, power and energy consumption in mobile platforms and data centers, and composition of heterogeneous simulations.