Parallel Ionic Liquid Semi-Packed Microfabricated Columns for Complex Gas Analysis

Abstract

The paper presents a parallel micro gas chromatography approach using three ionic liquid semipacked columns. Switching from single column to multiple parallel columns with different selectivity enhances the power of compound identification without increasing the analysis time. The columns are fabricated using microelectromechanical systems (MEMS) technology containing an array of microfabricated pillars. The columns are 1 m-long and 240 μm-deep with four pillars per row. All columns were functionalized with ionic liquid stationary phases using a modified static coating technique and demonstrated the number of theoretical plates between 5000 and 8300 per meter. The chip performance was investigated with four different samples: (1) a mixture of C7–C30 saturated alkanes, (2) a multianalyte mixture consisting of 20 compounds ranging from 80 to 238 °C in boiling point, (3) a mixture of five organic chemicals with varying degrees of polarity, and (4) 46-compounds mixture containing all the chemicals in the first three samples. The individual columns separated 75%–100% of the first three samples but failed to distinguish all 46 compounds due to coeluting analytes; however, the parallel configuration provided more retention time information by which all the compounds in all samples were fully determined.

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“…The HETP value corresponded to 4048 theoretical plates and 6747 plates/m. These values are comparable to other reported microfabricated columns [ 51 , 52 ]. Column3 provided similar performance for lower volatility analytes.…”

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