2022
DOI: 10.24132/csrn.3201.32
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Parallel YOLO-based Model for Real-time Mitosis Counting

Abstract: It is estimated that breast cancer incidences will increase by more than 50% by 2030 from 2011. Mitosis counting is one of the most commonly used methods of assessing the level of progression, and is a routine task for every patient diagnosed with invasive cancer. Although mitotic count is the strongest prognostic value, it is a tedious and subjective task with poor reproducibility, especially for non-experts. Object detection networks such as Faster RCNN have recently been adapted to medical applications to a… Show more

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Cited by 2 publications
(3 citation statements)
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“…The trained VGG16 based model, which had superior performance to the ResNet101 model, is available to anyone who wishes to access it under the name DeepSplashSpotter (DSS) [23]. Compared with existing blob detection algorithms [40][41][42][43][44][45] in medical images, the DSS can be applied to blob-like object detection problems where the blobs have low-contrast boundaries (not easily distinguished from background), are small relative to the image size, and are noisy.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The trained VGG16 based model, which had superior performance to the ResNet101 model, is available to anyone who wishes to access it under the name DeepSplashSpotter (DSS) [23]. Compared with existing blob detection algorithms [40][41][42][43][44][45] in medical images, the DSS can be applied to blob-like object detection problems where the blobs have low-contrast boundaries (not easily distinguished from background), are small relative to the image size, and are noisy.…”
Section: Discussionmentioning
confidence: 99%
“…Deep learning techniques are often applied to blob-like object detection in medical imaging e.g. U-Net deep learning models used for small biomarkers detection in magnetic resonance and fluorescent images [40,41], RCNNs [42] for blob detection and blob size prediction in cancer diagnosis and neuroimage processing [43][44][45]. In contrast to the blob-like objects that these algorithms have previously detected such as cell nuclei, the scintillation light splashes do not have clearly defined boundaries and instead gradually decrease in intensity at their edges before becoming indistinguishable from the background.…”
Section: Rcnn Methodsmentioning
confidence: 99%
“…The F1score reached 0.68 for ICPR14, making it the method that attained the highest score at this stage. R. Yancey [11] proposed the use of object detection networks such as YOLO (YOLOv3, YOLOv4scale, YOLOv5, and YOLOR) to improve the accuracy of mitosis counting. In these methods, the highest scores of 0.95 and 0.96 were achieved on the ICPR12 and ICPR14 mitosis datasets.…”
Section: Related Workmentioning
confidence: 99%