Introduction This article is a report of designing a rapid and effective guide for paramedics who take care of patients in a pre-hospital setting to answer developing demands.Methods The relevant literature was reviewed, and the topics were extracted. Then, the extracted items were discussed in an expert panel. Finally, items were discussed in a meeting including emergency technicians and emergency technical assistants to identify implementation problems.Result Important topics for managing psychiatric patients were categorized at three levels: 1) Patient safety and security issues, 2) Patient status assessment and diagnosis, and 3) Patient management (medical, behavioral management, and referral to a treatment center).Discussion This protocol can be a solution to improve emergency technician training. Such summarized protocols can be used for rapid review immediately before exposure to a patient with an acute psychiatric condition. Due to specific cultural and different access to medicines in Iran, some issues (For instant, access to medications) are different.