Consider a periodic, mean-reverting Ornstein-Uhlenbeck process X = {X t , t ≥ 0} of the form dX t = (L(t) + αX t ) dt + dB H t , t ≥ 0, where L(t) = p i=1 µ i φ i (t) is a periodic parametric function, and {B H t , t ≥ 0} is a fractional Brownian motion of Hurst parameter 1 2 ≤ H < 1. In the "ergodic" case α < 0, the parametric estimation of (µ 1 , . . . , µ p , α) based on continuous-time observation of X has been considered in Dehling et al. [5], and in Dehling et al. [6] for H = 1 2 , and 1 2 < H < 1, respectively. In this paper we consider the "non-ergodic" case α > 0, and for all 1 2 ≤ H < 1. We analyze the strong consistency and the asymptotic distribution for the estimator of (µ 1 , . . . , µ p , α) when the whole trajectory of X is observed.