Parameter interdependence and success of skeletal muscle modelling

Huijing, P.A.J.B.M.

doi:10.1016/0167-9457(95)00024-8

Cited by 41 publications

(26 citation statements)

References 132 publications

(130 reference statements)

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“…This means that, for the same muscle surface displacement, more force is detected at the tendon during the off-phase than during the on-phase diameter increase is not obvious given that not all the regions of a stimulated muscle change their absolute lateral position to the same extent. Other contributory factors include non-uniform distribution of the contractile elements (Frangioni et al 1987), a different distribution of fibre lengths (Zuurbier and Huijing 1993) and the different behaviour of the sarcomeres and aponeurosis (Huijing 1995) along the active muscle. With this in mind, the laser-detected MMG should be considered a mechanical signal reflecting part of the complex muscular morphological changes caused by different outcomes of the muscle fibres' activity.…”

Section: Discussionmentioning

confidence: 99%

Transients of the force and surface mechanomyogram during cat gastrocnemius tetanic stimulation

et al. 2003

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The aim of the study was to investigate the time relationship between force and muscle surface displacement, detected as the surface mechanomyogram (MMG) by a laser distance sensor, in the transient phases of a tetanic stimulation. For this purpose the motor nerve of the exposed medial gastrocnemius of four cats was supramaximally stimulated at 30, 40 and 50 Hz for 9 s. Force was detected by a transducer connected at the distal tendon while MMG was measured after pointing the laser beam at the muscle belly. We found that the MMG always anticipated and trailed the force changes during the on- and off-phase of the tetani, respectively. Independently of the stimulation rate, the half-times of the two signals were: on-phase, about 76 ms for force and 33 ms for MMG; off-phase, about 83 ms for force and 132 ms for MMG. There are two main comments to make about these results. First, during the on-phase the shortening of the contractile elements results at first in a muscle geometry change with low output force. After this, when the slack of the elastic-connective tissue has been taken up, the tension is efficiently transmitted to the tendon. Second, the different force and MMG dynamics in the on- and off-phases determine a counter-clockwise hysteresis with more force produced at a given muscle surface displacement during relaxation. To explain the results, the possible specific roles of some components of the muscle mechanical model, muscle mechanical properties and intra-muscular phenomena taking place during contraction have been discussed.

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Section: Discussionmentioning

confidence: 99%

Transients of the force and surface mechanomyogram during cat gastrocnemius tetanic stimulation

et al. 2003

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“…For muscle geometry this point has been argued on the basis of model considerations for many decades (Gans and Bock 1965;Huijing 1995;Huijing and Woittiez 1984;Kardell 1990;Otten 1988;Stensen 1667;Zuurbier and Huijing 1992). More recently the aspect of distribution of ®bre mean sarcomere length with respect to muscle length has also been emphasized (e.g.…”

Section: From Intact ®Bre Bundles To Whole Musclementioning

confidence: 97%

“…a 2-mm decrease in muscle length was also translated into a 2-mm decrease in ®bre bundle length, and the concomitant relative`muscle' force was then calculated from the ®bre bundle l±F curve obtained in the present study). Any eects of distribution of mean sarcomere length with respect to muscle length (Huijing 1995) were also ignored.…”

Section: From Intact ®Bre Bundles To Whole Musclementioning

confidence: 99%

Effects of in vivo-like activation frequency on the length-dependent force generation of skeletal muscle fibre bundles

Zuurbier

Groot

Laarse

et al. 1998

European Journal of Applied Physiology

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It is known that a range of firing frequencies can be observed during in vivo muscle activity, yet information is lacking as to how different in vivo-like frequencies may affect force generation of skeletal muscle. This study examined the effects of constant (CSF, constant within one contraction) and decreasing stimulation frequencies (DSF) on mean sarcomere length-force characteristics of rat gastrocnemius medialis fibre bundles. The CSF resulted in an optimal mean sarcomere length (lso) of 2.30 (SEM 0.02), 2.46 (SEM 0.03), 2.76 (SEM 0.03) and more than 2.99 (SEM 0.07) lm, for 100, 50, 30 and 15 Hz, respectively. Compared to 100-Hz stimulation, both lso and the ascending limb of the relationship significantly shifted to higher lengths with lower frequencies. No shift was encountered for the initial part of the descending limb. The DSF reduced the frequency-induced shift to higher mean lengths [lso 2.33 (SEM 0.02), 2.52 (SEM 0.08) and more than 2.92 (SEM 0.10) microm, respectively, for 50, 30 and 15 Hz]. No effect of activation time on length-force characteristics was observed. It was concluded from these studies that the frequency and history of stimulation is a major determinant of the length-force characteristics of muscle fibre bundles, and should be taken into account when analysing animal and human locomotion. The previously observed frequency-induced shift in whole muscle length-force relationship resides mainly at the level of fibre bundles.

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“…Changes in such distributions alter the muscle length range of active force exertion (i.e. the length range between the minimum and maximum length at which the muscle can still exert force) as well as optimal force [for a review see Huijing, 1995]. The effects of blunt dissection on EDL forces, as found in the present study, can be explained by opposing effects of a shift in active slack length as well as optimum length to a higher length, as found for EDL muscle in a previous study after excising TA and EHL muscles [Huijing and Baan, 2001a].…”

Section: Effects Of Blunt Dissection On Forces Exerted At the Tendonsmentioning

confidence: 99%

Intermuscular Interaction between Synergists in Rat Originates from both Intermuscular and Extramuscular Myofascial Force Transmission

Maas

Meijer

Huijing

2005

Cells Tissues Organs

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The purpose of the present study is to investigate the origin of mechanical interactions between the rat extensor digitorum longus (EDL) muscle and the grouped tibialis anterior and extensor hallucis longus muscles (TA+EHL). The proximal and distal tendons of EDL as well as the tied distal tendons of TA+EHL were transected and connected to force transducers. Connective tissues at the muscle bellies of the anterior crural compartment were left intact. Supramaximal stimulation of the common peroneal nerve activated all muscles maximally and simultaneously. Length-isometric force characteristics of distal TA+EHL were assessed. Simultaneously, forces exerted at the proximal and distal tendons of EDL, kept at constant muscle-tendon complex length and position, were measured. Intermuscular interaction was tested in two conditions: (a) after full longitudinal compartmental fasciotomy, and (b) after blunt dissection of the intermuscular connective tissue linkages between EDL and TA+EHL. Note that in the latter condition, intermuscular myofascial pathways were eliminated. In the initial condition, lengthening TA+EHL by 12 mm increased proximal (by 0.14 N, i.e. 9.5%) and decreased distal EDL force (by 0.21 N, i.e. 11.8%), despite the fact that EDL muscle-tendon complex length was kept constant. Blunt dissection decreased TA+EHL and distal EDL forces at low TA+EHL lengths only, while proximal EDL force decreased for all TA+EHL lengths tested. The dissection caused no changes in the TA+EHL length effects on proximal EDL force. In contrast, the amplitude of change in the distal EDL force curve decreased significantly (by 39%) subsequent to blunt dissection. It is concluded that mechanical interaction between synergists originates from both intermuscular as well as extramuscular connective tissues. The highest contribution, however, should be ascribed to the extramuscular pathway.

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Parameter interdependence and success of skeletal muscle modelling

Cited by 41 publications

References 132 publications

Transients of the force and surface mechanomyogram during cat gastrocnemius tetanic stimulation

Transients of the force and surface mechanomyogram during cat gastrocnemius tetanic stimulation

Effects of in vivo-like activation frequency on the length-dependent force generation of skeletal muscle fibre bundles

Intermuscular Interaction between Synergists in Rat Originates from both Intermuscular and Extramuscular Myofascial Force Transmission

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