Parameters Influencing the Outcome of Additive Manufacturing of Tiny Medical Devices Based on PEEK

Wang, Yiqiao; Müller, Wolf‐Dieter; Rumjahn, Adam; Schwitalla, Andreas Dominik

doi:10.3390/ma13020466

Cited by 69 publications

(54 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is worth noting that the electro-spinning approach has gained considerable attention from biomedical experts all around the world for manufacturing various polymers, particularly CS-based polymer scaffolds loaded with drugs for biomedical and wound dressing purposes [ 172 , 173 , 174 , 175 , 176 , 177 , 178 , 179 , 180 ]. Application of CS-based biopolymers through 3D [ 181 , 182 , 183 , 184 , 185 , 186 , 187 , 188 , 189 , 190 , 191 , 192 , 193 , 194 , 195 , 196 ] printing for biomedical purposes especially as bio-ink in an effort to fabricate complex tissues will probably be an upcoming pattern of 3D printing materials progression. However, CS and CS/Col designed bio-printed skin tissue has not already obtained the FDA approval, taking into account the similarity of constructed materials with some other permitted materials.…”

Section: Benefits Limitations and Future Prospectsmentioning

confidence: 99%

Three-Dimensional Printing Constructs Based on the Chitosan for Tissue Regeneration: State of the Art, Developing Directions and Prospect Trends

et al. 2020

View full text Add to dashboard Cite

Chitosan (CS) has gained particular attention in biomedical applications due to its biocompatibility, antibacterial feature, and biodegradability. Hence, many studies have focused on the manufacturing of CS films, scaffolds, particulate, and inks via different production methods. Nowadays, with the possibility of the precise adjustment of porosity size and shape, fiber size, suitable interconnectivity of pores, and creation of patient-specific constructs, 3D printing has overcome the limitations of many traditional manufacturing methods. Therefore, the fabrication of 3D printed CS scaffolds can lead to promising advances in tissue engineering and regenerative medicine. A review of additive manufacturing types, CS-based printed constructs, their usages as biomaterials, advantages, and drawbacks can open doors to optimize CS-based constructions for biomedical applications. The latest technological issues and upcoming capabilities of 3D printing with CS-based biopolymers for different applications are also discussed. This review article will act as a roadmap aiming to investigate chitosan as a new feedstock concerning various 3D printing approaches which may be employed in biomedical fields. In fact, the combination of 3D printing and CS-based biopolymers is extremely appealing particularly with regard to certain clinical purposes. Complications of 3D printing coupled with the challenges associated with materials should be recognized to help make this method feasible for wider clinical requirements. This strategy is currently gaining substantial attention in terms of several industrial biomedical products. In this review, the key 3D printing approaches along with revealing historical background are initially presented, and ultimately, the applications of different 3D printing techniques for fabricating chitosan constructs will be discussed. The recognition of essential complications and technical problems related to numerous 3D printing techniques and CS-based biopolymer choices according to clinical requirements is crucial. A comprehensive investigation will be required to encounter those challenges and to completely understand the possibilities of 3D printing in the foreseeable future.

show abstract

Section: Benefits Limitations and Future Prospectsmentioning

confidence: 99%

Three-Dimensional Printing Constructs Based on the Chitosan for Tissue Regeneration: State of the Art, Developing Directions and Prospect Trends

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In recent years, a huge amount of research effort has been devoted to studying polyetheretherketone(PEEK) and its application in the biomedical field [ 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 ]. Three-dimensional printing of PEEK is carried out via fused deposition modeling (FDM) or fused filament fabrication (FFF) and associated with significant challenges.…”

Section: Introductionmentioning

confidence: 99%

Indirect Temperature Measurement in High Frequency Heating Systems

Oskolkov

Bezukladnikov

Трушников

2021

Sensors

View full text Add to dashboard Cite

One of the biggest challenges of fused deposition modeling (FDM)/fused filament fabrication (FFF) 3D-printing is maintaining consistent quality of layer-to-layer adhesion, and on the larger scale, homogeneity of material inside the whole printed object. An approach for mitigating and/or resolving those problems, based on the rapid and reliable control of the extruded material temperature during the printing process, was proposed. High frequency induction heating of the nozzle with a minimum mass (<1 g) was used. To ensure the required dynamic characteristics of heating and cooling processes in a high power (peak power > 300 W) heating system, an indirect (eddy current) temperature measurement method was proposed. It is based on dynamic analysis over various temperature-dependent parameters directly in the process of heating. To ensure better temperature measurement accuracy, a series-parallel resonant circuit containing an induction heating coil, an approach of desired signal detection, algorithms for digital signal processing and a regression model that determines the dependence of the desired signal on temperature and magnetic field strength were proposed. The testbed system designed to confirm the results of the conducted research showed the effectiveness of the proposed indirect measurement method. With an accuracy of ±3 °C, the measurement time is 20 ms in the operating temperature range from 50 to 350 °C. The designed temperature control system based on an indirect measurement method will provide high mechanical properties and consistent quality of printed objects.

show abstract

“…Compared to SLS technology, material extrusion-based fused filament fabrication (FFF) technology is already integrated into the hospitals for the fabrication of anatomical biomodels, customized surgical tools, and prosthetic aids [ 9 ]. Besides, recent technological advancements in FFF 3D printers have made it possible to process high-temperature PEEK thermoplastic biomaterial [ 13 ]. In the FFF process, a filament is continuously extruded from a heated nozzle in a viscous state and deposited in a layer-by-layer manner to form the desired shape of an object.…”

Section: Introductionmentioning

confidence: 99%

“…This technology currently contributes to a new point-of-care (POC) workflow, implementing how PEEK medical implants need to be designed, developed, and manufactured for low-volume and on-demand production. Previous studies have demonstrated the feasibility of using FFF for medical PEEK printing [ 13 , 17 ]. As this technology is recognized as a prospective tool in the medical sector for in-hospital manufacturing of customized PEEK implants, the extent to which it affects the geometry and manufacturing quality remain under investigated.…”

Section: Introductionmentioning

confidence: 99%

Quality Characteristics and Clinical Relevance of In-House 3D-Printed Customized Polyetheretherketone (PEEK) Implants for Craniofacial Reconstruction

Sharma

Aghlmandi

Cao

et al. 2020

JCM

View full text Add to dashboard Cite

Additive manufacturing (AM) of patient-specific implants (PSIs) is gradually moving towards in-house or point-of-care (POC) manufacturing. Polyetheretherketone (PEEK) has been used in cranioplasty cases as a reliable alternative to other alloplastic materials. As only a few fused filament fabrication (FFF) printers are suitable for in-house manufacturing, the quality characteristics of the implants fabricated by FFF technology are still under investigated. This paper aimed to investigate PEEK PSIs fabricated in-house for craniofacial reconstruction, discussing the key challenges during the FFF printing process. Two exemplary cases of class III (Group 1) and class IV (Group 2) craniofacial defects were selected for the fabrication of PEEK PSIs. Taguchi’s L9 orthogonal array was selected for the following nonthermal printing process parameters, i.e., layer thickness, infill rate, number of shells, and infill pattern, and an assessment of the dimensional accuracy of the fabricated implants was made. The root mean square (RMS) values revealed higher deviations in Group 1 PSIs (0.790 mm) compared to Group 2 PSIs (0.241 mm). Horizontal lines, or the characteristic FFF stair-stepping effect, were more perceptible across the surface of Group 1 PSIs. Although Group 2 PSIs revealed no discoloration, Group 1 PSIs displayed different zones of crystallinity. These results suggest that the dimensional accuracy of PSIs were within the clinically acceptable range; however, attention must be paid towards a requirement of optimum thermal management during the printing process to fabricate implants of uniform crystallinity.

show abstract

Parameters Influencing the Outcome of Additive Manufacturing of Tiny Medical Devices Based on PEEK

Cited by 69 publications

References 31 publications

Three-Dimensional Printing Constructs Based on the Chitosan for Tissue Regeneration: State of the Art, Developing Directions and Prospect Trends

Three-Dimensional Printing Constructs Based on the Chitosan for Tissue Regeneration: State of the Art, Developing Directions and Prospect Trends

Indirect Temperature Measurement in High Frequency Heating Systems

Quality Characteristics and Clinical Relevance of In-House 3D-Printed Customized Polyetheretherketone (PEEK) Implants for Craniofacial Reconstruction

Contact Info

Product

Resources

About