Parameters of ultrasound examination of the abdominal cavity organs and kidneys in children and adolescents with connective tissue dysplasia

Суменко, В В; Лебедькова, С. Е.; Трусова, О Ю; Klimova, A. A.; Roschupkin, Anton; Savateevа, Arina

doi:10.14300/mnnc.2016.11057

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“…С другой стороны, имеющиеся особенности строения и функции соединительной ткани способствуют тому, что у пациентов с ДСТ легче и чаще возникают очаги нефросклероза, нарушение функции почек, возможно, с отдаленным итогом в виде хронической почечной недостаточности. В работах других исследователей встречаются данные о нарушениях гемодинамики в почках у пациентов с ДСТ, что также может быть патогенетически связано с несостоятельностью соединительной ткани [11,12,18,19]. ВЫВОДЫ 1.…”

Section: результаты и обс у ж дениеunclassified

Clinical and functional features of chronic pyelonephritis in children with connective tissue dysplasia

Иванова

Koval

2022

Pediatr (SPb)

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BACKGROUND: There is information in the literature about the effect of connective tissue dysplasia (СTD) on the course of many somatic diseases. The role of СTD in the development of chronic pyelonephritis (СhPN) is presented differently to different authors, which is why it became necessary to conduct this study. AIM: The aim of the work is to evaluate the effect of СTD on the course and manifestations of chronic secondary pyelonephritis in children. MATERIALS AND METHODS: 142 children from 6 to 17 years old with СhPN were examined. They were divided into 2 groups: the 1st group included 108 children with manifestations of СTD, including 41 people with СTD of the 3rd degree and 67 people with СTD of the 2nd degree; group 2 34 patients without СTD. The groups were comparable in gender and age. The examination was carried out according to the standards for patients with ChPN. Signs of СTD were evaluated by the method of T.I. Kadurina. RESULTS: Obstructive and mixed variants of СhPN are typical for children with СTD. In most patients, the disease manifested at 12 years of life; at school age the first signs of the disease occurred mainly in children without СTD with dysmetabolic disorders. Relapses of СhPN in children with СTD occurred 1.5 times more often during the year and 2,1 times more often during 5 years of follow-up. Patients with СTD are characterized by a wider range of pathogens, anemia, a high incidence of structural abnormalities and urodynamic disorders, a tendency to form foci of nephrosclerosis. The need for surgical treatment in the presence of СTD increases in patients with СhPN by 4.6 times, including in repeated and radical operations. In children with grade 3 СTD, all these signs are more represented. CONCLUSIONS: СTD affects the course and manifestations of СhPN in children, creating an unfavorable background. It seems promising to study the role of СTD in the occurrence of anemia in children with СhPN.

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Section: результаты и обс у ж дениеunclassified

Clinical and functional features of chronic pyelonephritis in children with connective tissue dysplasia

Иванова

Koval

2022

Pediatr (SPb)

View full text Add to dashboard Cite

show abstract

Parameters of ultrasound examination of the abdominal cavity organs and kidneys in children and adolescents with connective tissue dysplasia

Cited by 1 publication

References 0 publications

Clinical and functional features of chronic pyelonephritis in children with connective tissue dysplasia

Clinical and functional features of chronic pyelonephritis in children with connective tissue dysplasia

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