Paramètres hémodynamiques artériels et risque cardiovasculaire chez les patients vivant avec le VIH et en succès immuno-virologique

Yannoutsos, Alexandra; Ghosn, Jade; Blacher, Jacques

doi:10.1016/j.lpm.2017.12.003

Cited by 1 publication

(1 citation statement)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The determination of the augmentation index (AI) is a non-invasive method of its estimation. AI has been already used as a marker of subclinical atherosclerotic disease in people living with HIV [15]. We have been previously showed that HIV infection and cART had negative influence on arterial stiffness [16].…”

Section: Discussionmentioning

confidence: 99%

HIV-infected patients on combined antiretroviral treatment had similar level of arterial stiffness to the patients with ST-segment elevation myocardial infarction

Mikuła

Suchacz

Peller

et al. 2021

Preprint

View full text Add to dashboard Cite

BackgroundThe cardiovascular disease has become very common among HIV-infected patients.ObjectiveThe aim was to compare the arterial stiffness and the endothelial dysfunction in healthy HIV-infected patients to non-HIV-infected patients in week 4 after ST-segment elevation myocardial infarction (STEMI).MethodsThe arterial stiffness was calculated by Endo-PAT 2000 (ITAMAR®) and the endothelial function by Peripheral Arterial Tonometry (PAT®). The correct endothelial function was defined for natural logarithm of reactive hyperaemia index (lnRHI) > 0.51. Arterial stiffness was assessed as the AI and corrected for heart rate of 75 bpm (AI@75).ResultsSixty three patients were recruited to this study, 34 subjects with HIV infection (18 on cART) and 29 HIV-negative subjects after recent STEMI. AI was significantly higher in STEMI group than in HIV group. However, after AI@75 standardisation, no statistically significant difference was found between two studied groups. HIV-positive patients on cART had equally high values of arterial stiffness as persons after STEMI. The observed lnRHI results were significantly lower in STEMI group in comparison to HIV-positive patients, and the biggest significant difference was seen between STEMI group and ARV-treated HIV-infected patients.ConclusionsARV-treated HIV-infected patients may have similarly high values of arterial stiffness as non-HIV-infected persons in week 4 after STEMI. More larger studies are required to assess our observation concerning arterial stiffness and elevated risk of cardiovascular disease development in this group of patients, independently of age, smoking status and concomitant chronic diseases.

show abstract

Section: Discussionmentioning

confidence: 99%