Parametric evaluation for programmable temperature vaporisation large volume injection in gas chromatographic determination of polybrominated diphenyl ethers

Abstract

This work is a thorough investigation on the major operating parameters of the programmable temperature vaporization (PTV) inlet used for gas chromatographic injection, including injection mode and volume, inlet temperature, vent and purge flow rates. The results clearly demonstrate the advantage of large volume injection in enhancing the detection of polybrominated diphenyl ethers (PBDEs). Partial loss of injected PBDEs occurred during solvent venting and due to incomplete sample transfer. Such loss was minimized by lowering the initial inlet temperature and vent flow and elevating the final inlet temperature. The results show that 50 mL/min vent flow, as low as 0 °C initial and higher than 300 °C final inlet temperatures produced the relatively high responses. Two mass spectrometric parameters were also evaluated. Indoor dust, lake sediment and human placenta tissue samples were analyzed to demonstrate reliability and sensitivity improvement of the PTV large volume injection.

Recent development in analysis of persistent organic pollutants under the Stockholm Convention

“…To attain better sensitivity, Wei et al investigated different operating parameters of a programmable temperature-vaporization (PTV) inlet used in GC injection and enhanced PBDE detection by injecting 120 lL of sample solution [75]. The technique was illustrated by testing indoor dust SRM 2585, sediment, and placenta-tissue samples, and results demonstrated that PTV-GC-ECNI-MS was a sensitive, reliable approach for testing extremely low levels of PBDEs.…”

Polybromodiphenyl Ethers and Decabromodiphenyl Ethane in Aquatic Sediments from Southern and Eastern Arkansas, United States

“…A total of 49 PBDE congeners and DBDPE were analyzed on an Agilent 6890 gas chromatograph (GC) coupled with a 5973N mass spectrometer (MS) with electron capture negative ionization (ECNI). GC/MS parameters were optimized in our previous studies. , The MS was operated in selected ion monitoring (SIM) mode with m / z 486.6 and 488.6 for BDE209, 79, and 81 for other PBDEs, DBDPE, and BB209, and 510 and 512 for PCB209L.…”

“…GC/MS parameters were optimized in our previous studies. 21,22 The MS was operated in selected ion monitoring (SIM) mode with m/z 486.6 and 488.6 for BDE209, 79, and 81 for other PBDEs, DBDPE, and BB209, and 510 and 512 for PCB209L.…”

Particle size fractionation and human exposure of polybrominated diphenyl ethers in indoor dust from Chicago

“…The PTV operational parameters were optimized for PBDE analysis. [9] The initial oven temperature was 90 • C, which lasted for 3 min, and then increased to 140 • C at 10 • C/min and further to 300 • C at 5 • C/min. The final temperature was kept for 15 min until the run was completed.…”