Parapharyngeal metastases from thyroid cancer

Desuter, Gauthier; Lonneux, Max; Plouin‐Gaudon, Isabelle; Jamar, François; Coche, Edgard; Weynand, Birgit; Rahier, Jacques; Grégoire, Vincent; Andry, Guy; Hamoir, Marc

doi:10.1016/j.ejso.2003.10.004

Cited by 40 publications

(27 citation statements)

References 22 publications

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“…Totally, two relatively large numbers of DTC cases with parapharyngeal metastases have been described, suggesting that the incidence rate of parapharyngeal metastasis is extremely low (Desuter et al 2004). Parapharyngeal mass is often nonspecific or asymptomatic when the tumor does not exceed 3.0 cm in size (Tomoda et al 2005).…”

Section: Parapharyngeal Metastasismentioning

confidence: 99%

Rare metastases of differentiated thyroid carcinoma: pictorial review

Song

Xue²,

Xu³

et al. 2011

Endocrine-Related Cancer

131

148

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Differentiated thyroid cancer (DTC) is usually indolent with good prognosis and long-term survival. However, DTC distant metastasis is often a grave event and accounts for most of its diseasespecific mortality. The major sites of distant metastases are the lung and bone. Metastases to the brain, breast, liver, kidney, muscle, and skin are rare or relatively rare. Nevertheless, recognizing rare metastases from DTC has a significant impact on the clinical decision making and prognosis of patients.131 I single photon emission computed tomography/computed tomography ( 131 I-SPECT/CT) can provide both metabolic and anatomic information about a lesion; therefore, it can better localize and define the 131 I-WBS findings in DTC patients. In this pictorial review, the imaging features of a range of rare metastases from DTC are demonstrated, with a particular emphasis on the 131 I-SPECT/CT diagnostic aspect.

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Section: Parapharyngeal Metastasismentioning

confidence: 99%

Rare metastases of differentiated thyroid carcinoma: pictorial review

Song

Xue²,

Xu³

et al. 2011

Endocrine-Related Cancer

131

148

View full text Add to dashboard Cite

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“…Normally, these patients will complain of a mass in the neck or the oropharynx that causes dysphagia or even poorly specific symptoms such as headaches, temporomandibular-related pain, and snoring (20). These symptoms are usually due to the direct local infiltration of the tumor to the surrounding structures, depending on the degree of the infiltration to the trachea and esophagus (7,12).…”

Section: Discussionmentioning

confidence: 99%

“…According to Desuter et al (20), 30 cases of parapharyngeal thyroid carcinoma metastases have been reported in the last 3 decades (using the MEDLINE data base).…”

Section: Discussionmentioning

confidence: 99%

Unusual Papillary Thyroid Cancer Metastases to Kidney and Pharynx: A Case Report

Chen-Ku

Roldán

2016

AACE Clinical Case Reports

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Objective: The objective of this study is to report a very unusual case of papillary thyroid cancer with metastases to kidney and hematogenous spread to the pharynx.Methods: We reviewed all clinical data available for this patient, including computed tomography (CT) images and pathology samples. A literature search for kidney and pharynx metastases was performed in MEDLINE, using the terms "kidney metastases," "pharynx metastases," and "thyroid cancer." Relevant references were selected and reviewed.Results: A 50-year-old Hispanic woman with a history of papillary thyroid carcinoma (PTC), a total thyroidectomy, plus a modified radical neck dissection, who was treated on 2 separate occasions with 131 I (initially 100 mCi, and 1 year later 200 mCi), persisted with elevated thyroglobulin levels. An abdominal CT scan revealed a 3-cm lesion in the left kidney with no metastases to the lungs, bone, or liver. A left nephrectomy was performed. The pathology report confirmed metastases from PTC. Even then, thyroglobulin levels remained elevated. One year later, a CT scan was performed due to a chronic sinus infection, and it showed a mass in the right pharynx region. Fine-needle aspiration biopsy of this lesion reported metastases from PTC.Conclusion: PTC usually has a very indolent behavior. When metastasis is present it normally involves cervical nodes, lungs, or bone. In the medical literature, there are very few case reports of PTC metastases to kidney, such as in our case. To our knowledge, this is the first case report with kidney and pharynx involvement from a PTC. (AACE Clinical Case Rep. 2016;2:e86-e90) Abbreviations: CT = computed tomography; DTC = differentiated thyroid carcinoma; FTC = follicular thyroid carcinoma; NIS = sodium/iodide symporter; PTC = papillary thyroid carcinoma; Tg = thyroglobulin; TSH = thyrotropin

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“…A CT can be economical but MRI is superior for soft tissue imaging. The effective treatment of papillary thyroid carcinoma metastases into the local area is surgical resection (12). However, when residual thyroid tissue is left behind, a postoperative beam radiotherapy or radioablation are worth considering (8).…”

Section: Discussionmentioning

confidence: 99%

Hypopharyngeal and Parapharyngeal Space Metastasis of Papillary Thyroid Carcinoma: A Case Report

Batıoğlu-Karaaltın¹,

Azizli²,

Ersözlü³

et al. 2014

Balkan Med J

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Carcinoma of the thyroid gland is one of the most commonly encountered endocrine malignancies (1). Among all of the thyroid malignancies, papillary carcinoma is the most often encountered histological type and its pattern of metastasis is usually lymphatic (2). Around 30-80% of patients with papillary carcinoma develop lymphatic metastases (3). Haematogenic and distant metastases seem to be rare but, if present, the bone, lungs, skin, and brain are the most common localisations. Involvement of the recurrent laryngeal nerve, larynx, pharynx, trachea, and oesophagus occurs through direct infiltration (4, 5).Metastasis to the hypopharynx and parapharyngeal space seems to be straightforward due to the close anatomical localisation, but a few cases of parapharyngeal (6, 7) and hypopharyngeal involvement (8, 9) have appeared in the literature. In our case, we present papillary thyroid carcinoma metastasis involving both the hypopharynx and the parapharyngeal space. CASE PRESENTATIONA 70-year-old female patient was referred to our clinic with dysphagia and dyspnoea. The patient had undergone a total thyroidectomy ten years previously and the histological diagnosis was papillary thyroid carcinoma. Eight years after this surgery, a left modified radical neck dissection had been performed and histological examination showed papillary carcinoma metastasis in three lymph nodes. Indirect laryngoscopy revealed a sub-mucosal mass in the left lateral pharyngeal wall, which extended towards the midline. The larynx was deviated to the right and the left vocal cord was paralytic. Axial MRI section of the neck revealed a mass that was 2.4x1.3 cm in size narrowing the airway in the lateral wall of the hypopharynx. Sagittal MRI section of the neck showed that the mass was lining from the tracheal cartilage level to the parapharyngeal space ( Figure 1). The tumour was dissected upwards from the left sinus pyriformis and the great horn of the thyroid cartilage through the retropharyngeal space to the parapharyngeal space and the base of the skull. The 10 cm long tumour was excised totally (Figure 2). The hypopharyngeal defect was repaired with primary sutures. A histopathological evaluation showed a papillary structure under the epithelium. The diagnosis was a papillary carcinoma metastasis (Figure 3). Informed consent was taken from the patient.Background: Carcinoma of the thyroid gland is one of the most commonly encountered endocrine malignancies. Papillary carcinoma is the most common histological type, and its spread is usually lymphatic. About 30-80% patients with papillary carcinoma develop lymphatic metastases. Case Report: We present here the case of a 70-year-old female patient who had undergone total thyroidectomy 10 years previously, with a histological diagnosis of papillary thyroid carcinoma. A neck dissection was performed ten years after the primary operation due to a mass in the parapharyngeal space and hypopharynx. The mass was diagnosed histologically as papillary thyroid cancer metastasis after the operation. Concl...

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Parapharyngeal metastases from thyroid cancer

Cited by 40 publications

References 22 publications

Rare metastases of differentiated thyroid carcinoma: pictorial review

Rare metastases of differentiated thyroid carcinoma: pictorial review

Unusual Papillary Thyroid Cancer Metastases to Kidney and Pharynx: A Case Report

Hypopharyngeal and Parapharyngeal Space Metastasis of Papillary Thyroid Carcinoma: A Case Report

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