“…This mechanism would be very similar to the situation encountered at the lumbar level, in which the passage of upper lumbar ISAs through the crus of the diaphragm 2 occasionally results in extrinsic compression, leading to spinal cord ischemia when the involved vessel provides a significant spinal artery contributor. 1,25 Although surgical treatment can be offered at the lumbar level, with the compression being relieved by section of the pillar of the diaphragm, there is at this time no straightforward method addressing the upper thoracic ISA stenoses described in the present report. Several patients presenting with progressive or recurrent myelopathies of unclear etiologies, and in whom a stenosis or occlusion was shown to involve an ISA providing a prominent anterior RMA, were placed on prophylactic antiplatelet therapy with aspirin and/or clopidogrel.…”