Parasitic Infections of the Central Nervous System

Brutto, Oscar H. Del

doi:10.1007/978-1-4471-6401-2_9

Cited by 3 publications

(7 citation statements)

References 31 publications

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“…Bacterial infections of the CNS are a highly crucial global health issue because of the high level of associated morbidity and mortality [13]. Almost any CNS bacterial infection can result in ASyS and subsequent risk of acquired epilepsy [14-16]. Key moderators in amplifying the risk of development of epilepsy are the age at the time of infection as well as the presence of a family history of epilepsy, alluding to the significant role that genetic factors and brain maturation contribute in this regard [15, 16].…”

Section: Bacterial Infections As a Cause Of Seizures/epilepsymentioning

confidence: 99%

“…Seizures as the presenting symptom have been reported to occur in 25‐34% of patients [28, 29]. Cerebral abscesses are usually associated with predisposing factors such as sinusitis, otitis media, dental abscesses, congenital heart disease with right‐to‐left shunt, and pulmonary infection [14, 15], and sometimes, an etiology cannot be identified. Streptococcus and Staphylococcus species are implicated in the vast majority of bacterial brain abscesses, although anaerobic bacteria such as Bacteroides , Fusobacterium , Prevotella, and Actinomyces species are also key pathogens, and about a quarter of cases are due to polymicrobial agents.…”

Section: Bacterial Infections As a Cause Of Seizures/epilepsymentioning

confidence: 99%

“…Direct implantation of pathogens may follow from congenital defects such as myelomeningoceles, a trauma in penetrating injuries, and compound skull fractures or ensue from surgical procedures as well as invasive diagnostic and therapeutic interventions. CNS tuberculosis is usually caused by Mycobacterium tuberculosis which reaches the brain by the hematogenous route from the lungs [15].…”

Section: Bacterial Infections As a Cause Of Seizures/epilepsymentioning

confidence: 99%

See 2 more Smart Citations

Common infectious and parasitic diseases as a cause of seizures: geographic distribution and contribution to the burden of epilepsy

Yacubian¹,

Kakooza‐Mwesige²,

Singh³

et al. 2022

Epileptic Disorders

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This educational review article aims to provide information on the central nervous system (CNS) infectious and parasitic diseases that frequently cause seizures and acquired epilepsy in the developing world. We explain the difficulties in defining acute symptomatic seizures, which are common in patients with meningitis, viral encephalitis, malaria, and neurocysticercosis, most of which are associated with increased mortality and morbidity, including subsequent epilepsy. Geographic location determines the common causes of infectious and parasitic diseases in a particular region. Management issues encompass prompt treatment of acute symptomatic seizures and the underlying CNS infection, correction of associated predisposing factors, and decisions regarding the appropriate choice and duration of antiseizure therapy. Although healthcare provider education, to recognize and diagnose seizures and epilepsy related to these diseases, is a feasible objective to save lives, prevention of CNS infections and infestations is the only definitive way forward to reduce the burden of epilepsy in developing countries.

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Section: Bacterial Infections As a Cause Of Seizures/epilepsymentioning

confidence: 99%

Section: Bacterial Infections As a Cause Of Seizures/epilepsymentioning

confidence: 99%

Section: Bacterial Infections As a Cause Of Seizures/epilepsymentioning

confidence: 99%

See 1 more Smart Citation

Common infectious and parasitic diseases as a cause of seizures: geographic distribution and contribution to the burden of epilepsy

Yacubian¹,

Kakooza‐Mwesige²,

Singh³

et al. 2022

Epileptic Disorders

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“…After ingestion, the eggs hatch in the duodenum and release larvae that can penetrate intestinal mucosa and enter the circulatory system, by which they localize as cysts within the skeletal muscles, eyes, or brain (1) . When a larva is detected in the nervous system, this clinical manifestation is named as neurocysticercosis, which is the most common helminthic infection of the central nervous system (3) .…”

Section: Case Reportmentioning

confidence: 99%

Neurocysticercosis: A Rare Cause of Occipital Lobe Epilepsy

Küçükyürük

Tanrıverdi

Öz³

et al. 2014

sscd

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Thirteen-year-old boy admitted to our clinic because of intractable occipital lobe epilepsy and underwent surgical resection of epileptogenic focus at the left occipital lobe. Histopathological examinations revealed a parasitic infestation, neurocystocercosis. After surgery the patient was seizurefree at short-term follow-up and referred to the outpatient clinic of Infectious Diseases for futher medical treatment of taenia solium. A case of intractable occipital lobe epilepsy due to cysticersosus was discussed with possible pitfalls in diagnosis.

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“…Toxocariasis is related to asthma, pulmonary inflammation, and eosinophilia in children. In addition, some of the complications of toxocariasis in the central nervous system have been reported as convulsions and mental and growth retardation ( 3 , 8 , 9 ). The migration of Toxocara larva to the eye (OLM) causes reduced visual acuity, strabismus, and, in some cases, blindness in one or both eyes due to granulomatous lesions in the retina.…”

Section: Introductionmentioning

confidence: 99%

Seroepidemiological Study of Toxocariasis in Children Aged 6-14 Year Old in Sanandaj, Western Iran

Maroufi

Faridi

Erfan

et al. 2020

IJPA

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Background: Toxocariasis is a disease caused by Toxocara nematodes and occurs from consuming their eggs. The main hosts of these worms are dogs and cats. The disease in humans becomes a visceral larva migrans (VLM). This descriptive cross-sectional study was conducted to determine the prevalence of toxocariasis in children aged 6–14 years. Methods: This cross-sectional descriptive study was conducted from Jun 1 2016 to Dec 1 2017 in Sanandaj, west of Iran. A total of 182 serum samples were collected from children age 6 to14 yr referred to medical diagnostic laboratories. Demographic data (age, sex, and parents' literacy status), clinical signs (cough, headache, fever, abdominal pain), and the history of contact with dogs and cats was collected by a questionnaire. The presence of anti-Toxocara IgG antibody was detected by T. canis IgG ELISA (IBL, Germany) kit. Results: Of 182 subjects, 97 (53.3%) were male and 85 (46.7%) female. The average age was 9.2 years. Antibodies against T. canis were positive in three cases (1.65%) of all the studied subjects. Conclusions: The results showed a low prevalence of toxocariasis in children studied.

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Parasitic Infections of the Central Nervous System

Cited by 3 publications

References 31 publications

Common infectious and parasitic diseases as a cause of seizures: geographic distribution and contribution to the burden of epilepsy

Common infectious and parasitic diseases as a cause of seizures: geographic distribution and contribution to the burden of epilepsy

Neurocysticercosis: A Rare Cause of Occipital Lobe Epilepsy

Seroepidemiological Study of Toxocariasis in Children Aged 6-14 Year Old in Sanandaj, Western Iran

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