“…Studies have varied as to whether the prophylactic mesh was placed in an onlay, retromuscular, or intraperitoneal position. There does not appear to be any strong evidence to support any one method over another at this time (table 4) [94,96,98,99,100,101,102,103,104,105]. A recent cost-effectiveness analysis also demonstrated cost savings and improvement in effectiveness for patients with Stage I to III rectal cancer undergoing APR with prophylactic mesh placement [106].…”