Paratesticular Papillary Mesothelioma

Abstract

A case of uncommon paratesticular mesothelioma in a young patient is presented. Its questionable malignancy, as well as the method of treatment are discussed.

Para- and Intratesticular Aspects of Malignant Mesothelioma

“…Other possible etiological factors that have been suggested for malignant disease include previous testicular trauma and hernia repair; however these factors have not been corroborated (Amin, 1995;Antman et al, 1984). In the few cases reported in patients in the first three decades of life, no history of asbestos exposure was reported in the patient or family and the etiological factor in these cases remains unclear (Antman et al, 1984;Johnson et al, 1973;Jones et al, 1995;Linn et al, 1988;McDonald et al, 1983;Plas et al, 1998;Stein and Henkes, 1986).…”

Well-differentiated Papillary Mesothelial Tumour of the Tunica Vaginalis Testis – A Rare Lesion, but one Pathologists Should Know About Two Patient Reports and a Review of the Literature

“…More commonly found in the peritoneal cavity, these neoplasms, referred to as well-differentiated papillary mesothelial tumor (WDPMT) or well-differentiated papillary mesothelioma (WDPM), are rarely seen in the testis. Initially described in 1957 by Bárbera et al, a few dozen such tumors have to date been reported in the literature, one of the most important series reported being the work of Brimo et al [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] Typically, these neoplasms show no architectural complexity, whereas borderline tumors with more complex architectures or areas of uncertain invasion are reported and pose a diagnostic challenge as there is an ongoing debate about whether to classify these as benign or of uncertain malignant potential, with consequences for further patient management and patient perception of their illness. 4,5,8,15 In recent years, new molecular analytical tools, including BAP1 immunohistochemistry, have emerged, probably aiding in the diagnostic classification.…”