Parathyroid Adenoma Mimicking Tuberculosis in a Peritoneal Dialysis Patient

Şirali, Semahat Karahisar; Tomar, Özdem Kavraz; Büberci, Refika; Bal, Amanjit; Duranay, Murat

doi:10.4183/aeb.2022.225

Cited by 1 publication

(1 citation statement)

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“…Granulomatous disorders are a type of chronic inflammation caused by autoimmune diseases, allergies, infections, toxins, and neoplastic conditions (3). Tuberculosis (TB) and sarcoidosis are common granulomatous diseases that rarely affect the parathyroid gland and their co-occurrence with a functioning parathyroid adenoma leading to hypercalcemia is extremely uncommon (4,5). Vitamin D [1,25(OH) 2 D 3 ]-mediated granulomatous disorder, along with osteoclast activation within the bones, is the leading cause of high serum levels of calcium.…”

Section: Introductionmentioning

confidence: 99%

Tuberculous granulomatous inflammation of parathyroid adenoma manifested as primary hyperparathyroidism: A case report and a review of the literature

Salih,

Qaradakhy,

Hassan

et al. 2023

Med Int

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tuberculosis of the thyroid gland is rare, and tuberculous granulomatous inflammation of the parathyroid glands is even rarer. The present study reports a rare case of primary hyperparathyroidism caused by tuberculous granulomatous inflammation. A 58-year-old female patient presented with generalized body pain persisting for 1 year. She had a history of recurrent renal stones (>20 times) and an incidental finding of multinodular goiter involving the parathyroid on neck ultrasound. a blood analysis revealed elevated levels of serum calcium (11.26 mg/dl) and parathyroid hormone (154.7 pg/ml). The patient underwent the resection of the affected left thyroid lobe under general anesthesia. a histopathological examination revealed parathyroid adenoma with caseating granulomatous inflammation involving the adenoma with focal lymphocytic thyroiditis of the left thyroid gland. Although granulomatous parathyroid disease with parathyroid adenoma causing hypercalcemia is an extremely rare event, it can occur. the treatment of choice is surgical resection.

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Section: Introductionmentioning

confidence: 99%