Parathyroid Cystic Adenoma: A Systematic Review and Meta-Analysis

Daoud, Amani; Ronen, Ohad

doi:10.1016/j.eprac.2022.11.004

Cited by 6 publications

(3 citation statements)

References 63 publications

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“…Most cases, especially those caused by non-functional cysts, are diagnosed incidentally during imaging examination (ultrasound-US, computed tomography-CT, single-photon emission computed tomography-computed tomography-SPECT-CT) [6,10,20,21]. In our patients the US and SPECT-CT were performed.…”

Section: Discussionmentioning

confidence: 96%

“…The authors used the PubMed and Cochrane databases to search for articles that were published between 1995 and 2020. The review gathered up to 39 studies with a total of 160 patients, diagnosed mainly with a single cystic adenoma [6].…”

Section: Discussionmentioning

confidence: 99%

“…Parathyroid cysts occur rarely, representing 0.5-1% of parathyroid lesions [6,7]. The first information concerning this condition dates back to 1880, and since then, less than 400 cases have been reported [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

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Cystic Parathyroid Adenomas as a Risk Factor for Severe Hypercalcemia

Kaszczewska

Chudziński

Kaszczewski

et al. 2023

JCM

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(1) Background: Parathyroid cystic adenomas (PCA) are rare entities representing only 0.5–1% of parathyroid adenomas, accounting for 1–2% of cases of primary hyperparathyroidism (PHPT). The purpose of this study was to compare classical and functional/secreting cystic parathyroid lesions and identify risk factors for severe hypercalcemia; (2) Methods: A total of 17 patients with PHPT and parathyroid cysts (study group) were compared with the group of 100 patients with hyperparathyroidism caused by adenoma or hyperplasia (control group). In both groups the majority were women (88% vs. 12%, with gender ratio 7, 3:1). The patients were examined preoperatively and postoperatively: PTH, creatine, calcium and phosphate serum and urine concentrations and calcidiol serum levels were assessed; (3) Results: Patients with parathyroid cyst had statistically higher PTH and calcium serum concentration, higher calciuria and lower serum phosphate concentration. There were no statistically significant differences in the concentration of creatine in serum and urine and tubular reabsorption of phosphorus (TRP); (4) Conclusions: Due to higher PTH and calcium levels, cystic parathyroid adenomas could be one of the rare risk factors for severe hypercalcemia and hypercalcemic crisis which can be life threatening.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%