Parathyroid Hormone and Vitamin D Levels in Obstructive Sleep Apnea

Krasimirova, Daniela; Bilyukov, Radoslav; Pencheva, Ventsislava; Петрова, Даниела; Mondeshki, Tzanko; Georgiev, Ognian; Nikolov, M.; Tsakova, Adelina

doi:10.1183/1393003.congress-2017.pa2335

Cited by 1 publication

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“… 15 Another study showed that patients with obstructive sleep apnea had significantly higher serum levels of PTH (5.93 ± 1.82 pmol/L) compared to controls (3.13 ± 0.97 pmol/L), p < 0.001. 16 Among the various environmental and lifestyle factors known to affect PTH secretion, diet is one of them. 6 Fasting could lead to a reduction in calcium, which can increase PTH concentration; in the same vein, a heavy meal following evening prayer after breaking the day’s fasting can lead to an increase in post-absorptive calcium concentration, which can reduce PTH.…”

Section: Discussionmentioning

confidence: 99%

A case report of primary hyperparathyroidism in an adolescent during Ramadan fast

Eze,

Elfadil

2024

SAGE Open Medical Case Reports

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Primary hyperparathyroidism is rare in children and usually presents with nonspecific symptoms. Ramadan fasting has been reported to unmask the diagnosis of primary hyperparathyroidism. A 15-year-old boy presented to the clinic for an emergency department follow up visit. He had started Ramadan fasting a week before his presentation to the clinic. He reported unintentional weight loss, abdominal pain, constipation, frequent headaches, exercise intolerance, tiredness, and palpitations. Physical examination was unremarkable except that he looked tired. Investigations revealed elevated calcium and parathyroid hormone, hypophosphatemia, low vitamin D, and parathyroid adenoma. He underwent parathyroidectomy, leading to a decrease in parathyroid hormone levels. He did well postoperatively, and by his 11-month follow-up visit, his calcium was back to a normal level, he was energetic, and had gained weight. A high index of suspicion is required to diagnose primary hyperparathyroidism in young patients, especially young Ramadan-fasting patients, who mostly present with vague nonspecific symptoms.

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Section: Discussionmentioning

confidence: 99%