Parathyroid lipoadenoma: The particularities of a rare entity a case report and review of the literature

Mohamed, Amine Mennouni; Oukessou, Youssef; Bouhmadi, Khadija El; Rouadi, Sami; Abada, R.; Mahtar, Mohamed

doi:10.1016/j.ijscr.2021.01.091

Cited by 6 publications

(1 citation statement)

References 13 publications

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“…Parathyroid lipoadenomas are rare and are incidentally detected during thyroid cancer surgery in this case. The article reports 40 cases of parathyroid lipoadenoma reported in PubMed from 1962 to date using the search terms “parathyroid lipoadenoma” and “parathyroid lipoadenoma”, 1 , 2 , 4 , 5 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 of which 65 cases of parathyroid lipoadenoma were reported (including this case). After excluding 18 cases with missing clinical data, 47 cases had complete clinical data, including 30 females and 17 males, with a female‐to‐male ratio of about 1.8:1, that is, parathyroid lipoadenoma accounted for a higher proportion in females than in males.…”

Section: Discussionmentioning

confidence: 99%

Incidentally discovered parathyroid lipoadenoma in thyroid surgery: A case report and review of the literature

Wang,

Chen,

2023

Clinical Case Reports

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Key Clinical MessageParathyroid lipoadenoma is a rare type of parathyroid adenoma, described as a single parathyroid adenoma with more than 50% fat on histologic examination and an unknown etiology, which is one of the rare causes of primary hyperparathyroidism. The difficulty of parathyroid lipoadenoma is mainly diagnosed by preoperative imaging localization. We hope to arouse attention to the parathyroid adenoma which is difficult to locate through our case report. The patient was a middle‐aged male with a body mass index of 38.4 kg/m2 who admitted to our hospital with a 40‐day history of an untreated thyroid nodule. We incidentally discovered parathyroid lipoadenoma in his thyroid surgery. His prognosis was good, and there were no signs of recurrence at his 12‐month follow‐up appointment. We believe that parathyroid lipoadenoma needs to rely on paraffin pathology to make a final diagnosis. This case report serves as a reminder that parathyroid lipoadenomas are also possible in patients who do not have primary hyperparathyroidism preoperatively and who have negative imaging. Clinicians must carefully examine the adipose tissue for the presence of parathyroid lipoadenomas during thyroid surgery to avoid postoperative hypoparathyroidism and persistent hypocalcaemia.

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