Paratracheal Extramedullary Hematopoiesis

Kurtman, Cengiz; Özbilgin, Mahmut Kemal; Andrieu, Meltem Nalca; Çelebioğlu, Binnaz

doi:10.1007/bf02994012

Cited by 8 publications

(4 citation statements)

References 30 publications

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“…In very rare cases, EMH may involve the pleura and the pleural and pericardial spaces. Although patients are usually asymptomatic, there are rare cases with spontaneous hemothorax 1,24 …”

Section: Thoraxmentioning

confidence: 99%

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Extramedullary Hematopoiesis: A Forgotten Diagnosis and a Great Mimicker of Malignancy

Fouladi

Fishman

Kawamoto

2023

J Comput Assist Tomogr

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Radiology errors have been reported in up to 30% of cases when patients have abnormal imaging findings. Although more than half of errors are failures to detect critical findings, over 40% of errors are when findings are recognized but the correct diagnosis or interpretation is not made. One common source of error is when imaging findings from one process simulate imaging findings from another process but the correct diagnosis is not made. This can result in additional imaging studies, unnecessary biopsies, or surgery. Extramedullary hematopoiesis is one of those uncommon disease processes that can produce many imaging findings that may lead to misdiagnosis. The objective of this article is to review the common and uncommon imaging features of extramedullary hematopoiesis while presenting a series of interesting relevant illustrative cases with emphasis on CT.

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“…In very rare cases, EMH may involve the pleura and the pleural and pericardial spaces. Although patients are usually asymptomatic, there are rare cases with spontaneous hemothorax 1,24 …”

Section: Thoraxmentioning

confidence: 99%

“…Although patients are usually asymptomatic, there are rare cases with spontaneous hemothorax. 1,24 ABDOMEN AND PELVIS…”

Section: Paraspinal and Posterior Mediastinal Areasmentioning

confidence: 99%

Extramedullary Hematopoiesis: A Forgotten Diagnosis and a Great Mimicker of Malignancy

Fouladi

Fishman

Kawamoto

2023

J Comput Assist Tomogr

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“… Paratracheal EMH presenting with severe progressive dyspnoea and treated successfully with radiotherapy 15 EMH involving pre‐cardiac and pleural spaces 4 EMH can rarely involve the kidneys, presenting as parapelvic haematopoietic masses 4 EMH has been reported in other very rare locations, such as the gastrointestinal tract, urinary tract, adrenal glands, central nervous system, prostate, peritoneum, skin, breast, middle ear and lacrimal glands 3,14 …”

Section: Atypical Emh Locationsmentioning

confidence: 99%

“…Paratracheal EMH presenting with severe progressive dyspnoea and treated successfully with radiotherapy 15 …”

Section: Atypical Emh Locationsmentioning

confidence: 99%

Extra‐medullary haematopoiesis: A pictorial review of its typical and atypical locations

Lau²,

et al. 2012

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SummaryExtra-medullary haematopoiesis (EMH) occurs in many haematological disorders and is secondary to insufficient bone marrow function or ineffective erythropoiesis. It usually presents as haematopoietic masses in several typical and atypical body locations. This pictorial review briefly discusses the common EMH locations encountered in clinical practice, including the liver, spleen, lymph nodes and paravertebral regions. Unusual presentation as focal hepatic and splenic masses is also discussed. Some atypical EMH locations are then presented together with their pathophysiology and relevant illustrations. These include EMH in the intra-spinal canal, pre-sacral region, nasopharynx and paranasal sinuses. Intra-spinal EMH can cause cord compression and present with neurological symptoms. In these cases, urgent treatment may be required. Haematopoietic masses in the other atypical locations can present with obstructive symptoms or may be diagnosed incidentally on imaging. EMH in unusual locations need to be monitored with follow-up imaging to ensure their stability. In some circumstances, tissue biopsy is appropriate to confirm the diagnosis and exclude other sinister pathology (e.g. malignancy). Treatment is only required where symptoms are present. Management options include blood transfusion, radiotherapy, hydroxyurea or surgical resection in selected cases.

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Clinical and imaging findings in thalassemia patients with extramedullary hematopoiesis

Zhu

Zhang

et al. 2012

Clinical Imaging

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Paratracheal Extramedullary Hematopoiesis

Cited by 8 publications

References 30 publications

Extramedullary Hematopoiesis: A Forgotten Diagnosis and a Great Mimicker of Malignancy

Extramedullary Hematopoiesis: A Forgotten Diagnosis and a Great Mimicker of Malignancy

Extra‐medullary haematopoiesis: A pictorial review of its typical and atypical locations

Clinical and imaging findings in thalassemia patients with extramedullary hematopoiesis

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