Paraviral bullous eruption in a 7‐year‐old child during acute Epstein–Barr virus infection: A case report

Abstract

Bullous eruptions in children can be a diagnostic challenge even for the most experienced clinician. In fact, they encompass a wide range of entities, including acquired and congenital disorders.It is well recognized that viral infections can act as trigger factors for bullous diseases in adults, while few data are available in children. [1][2][3] In this regard, it is postulated that autoimmune bullous disorders develop following an interaction between genetic and environmental factors. Various members of the human herpes virus (HHV) family may act as potential triggers or exacerbators of pemphigus vulgaris. Among these viruses are included varicella zoster virus (VZV), herpes simplex virus (HSV), cytomegalovirus (CMV), human herpes virus 8 (HHV 8), and Epstein-Barr virus (EBV). [4][5][6] In this article, we present the case of a 7-year-old girl developing widespread vesicle-bullous lesions after an acute and symptomatic EBV infection, in the presence of both virus-specific IgG and IgM. | CASE HISTORYA 7-year-old female child was referred to our Pediatric Dermatology Unit following several dermatological consultations with the suspect of monkey-pox infection. General conditions were good and objective examination was negative apart from retroauricular lymphadenopathy. The mother reported only few acute episodes of mild cough in the previous 10 days.Skin inspection revealed a diffuse vesicle-bullous eruption, with involvement of neck and face and sparing of